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A new family of bacterial ribosome hibernation factors.
Helena-Bueno K, Rybak MY, Ekemezie CL, Sullivan R, Brown CR, Dingwall C, Baslé A, Schneider C, Connolly JPR, Blaza JN, Csörgő B, Moynihan PJ, Gagnon MG, Hill CH, Melnikov SV. Helena-Bueno K, et al. Among authors: moynihan pj. Nature. 2024 Feb;626(8001):1125-1132. doi: 10.1038/s41586-024-07041-8. Epub 2024 Feb 14. Nature. 2024. PMID: 38355796 Free PMC article.
Identification of D-arabinan-degrading enzymes in mycobacteria.
Al-Jourani O, Benedict ST, Ross J, Layton AJ, van der Peet P, Marando VM, Bailey NP, Heunis T, Manion J, Mensitieri F, Franklin A, Abellon-Ruiz J, Oram SL, Parsons L, Cartmell A, Wright GSA, Baslé A, Trost M, Henrissat B, Munoz-Munoz J, Hirt RP, Kiessling LL, Lovering AL, Williams SJ, Lowe EC, Moynihan PJ. Al-Jourani O, et al. Among authors: moynihan pj. Nat Commun. 2023 Apr 19;14(1):2233. doi: 10.1038/s41467-023-37839-5. Nat Commun. 2023. PMID: 37076525 Free PMC article.
The mycobacterial glycoside hydrolase LamH enables capsular arabinomannan release and stimulates growth.
Franklin A, Layton AJ, Mize T, Salgueiro VC, Sullivan R, Benedict ST, Gurcha SS, Anso I, Besra GS, Banzhaf M, Lovering AL, Williams SJ, Guerin ME, Scott NE, Prados-Rosales R, Lowe EC, Moynihan PJ. Franklin A, et al. Among authors: moynihan pj. bioRxiv [Preprint]. 2023 Oct 26:2023.10.26.563968. doi: 10.1101/2023.10.26.563968. bioRxiv. 2023. PMID: 37961452 Free PMC article. Preprint.
The hydrolase LpqI primes mycobacterial peptidoglycan recycling.
Moynihan PJ, Cadby IT, Veerapen N, Jankute M, Crosatti M, Mukamolova GV, Lovering AL, Besra GS. Moynihan PJ, et al. Nat Commun. 2019 Jun 14;10(1):2647. doi: 10.1038/s41467-019-10586-2. Nat Commun. 2019. PMID: 31201321 Free PMC article.
Identification of KasA as the cellular target of an anti-tubercular scaffold.
Abrahams KA, Chung CW, Ghidelli-Disse S, Rullas J, Rebollo-López MJ, Gurcha SS, Cox JA, Mendoza A, Jiménez-Navarro E, Martínez-Martínez MS, Neu M, Shillings A, Homes P, Argyrou A, Casanueva R, Loman NJ, Moynihan PJ, Lelièvre J, Selenski C, Axtman M, Kremer L, Bantscheff M, Angulo-Barturen I, Izquierdo MC, Cammack NC, Drewes G, Ballell L, Barros D, Besra GS, Bates RH. Abrahams KA, et al. Among authors: moynihan pj. Nat Commun. 2016 Sep 1;7:12581. doi: 10.1038/ncomms12581. Nat Commun. 2016. PMID: 27581223 Free PMC article.
107 results