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Improving amphetamine therapeutic selectivity: N,N-dimethyl-MTA has dopaminergic effects and does not produce aortic contraction.
Sotomayor-Zárate R, Jara P, Araos P, Vinet R, Quiroz G, Renard GM, Espinosa P, Hurtado-Guzmán C, Moya PR, Iturriaga-Vásquez P, Gysling K, Reyes-Parada M. Sotomayor-Zárate R, et al. Among authors: moya pr. Basic Clin Pharmacol Toxicol. 2014 May;114(5):395-9. doi: 10.1111/bcpt.12168. Epub 2013 Dec 7. Basic Clin Pharmacol Toxicol. 2014. PMID: 24314229 Free article.
N,N-dimethyl-thioamphetamine and methyl-thioamphetamine, two non-neurotoxic substrates of 5-HT transporters, have scant in vitro efficacy for the induction of transporter-mediated 5-HT release and currents.
Gobbi M, Funicello M, Gerstbrein K, Holy M, Moya PR, Sotomayor R, Forray MI, Gysling K, Paluzzi S, Bonanno G, Reyes-Parada M, Sitte HH, Mennini T. Gobbi M, et al. Among authors: moya pr. J Neurochem. 2008 Jun;105(5):1770-80. doi: 10.1111/j.1471-4159.2008.05272.x. Epub 2008 Feb 4. J Neurochem. 2008. PMID: 18248615 Free PMC article.
4-Methylthioamphetamine increases dopamine in the rat striatum and has rewarding effects in vivo.
Sotomayor-Zárate R, Quiroz G, Araya KA, Abarca J, Ibáñez MR, Montecinos A, Guajardo C, Núñez G, Fierro A, Moya PR, Iturriaga-Vásquez P, Gómez-Molina C, Gysling K, Reyes-Parada M. Sotomayor-Zárate R, et al. Among authors: moya pr. Basic Clin Pharmacol Toxicol. 2012 Dec;111(6):371-9. doi: 10.1111/j.1742-7843.2012.00926.x. Epub 2012 Aug 31. Basic Clin Pharmacol Toxicol. 2012. PMID: 22788961 Free article.
Behavioral and synaptic alterations relevant to obsessive-compulsive disorder in mice with increased EAAT3 expression.
Delgado-Acevedo C, Estay SF, Radke AK, Sengupta A, Escobar AP, Henríquez-Belmar F, Reyes CA, Haro-Acuña V, Utreras E, Sotomayor-Zárate R, Cho A, Wendland JR, Kulkarni AB, Holmes A, Murphy DL, Chávez AE, Moya PR. Delgado-Acevedo C, et al. Among authors: moya pr. Neuropsychopharmacology. 2019 May;44(6):1163-1173. doi: 10.1038/s41386-018-0302-7. Epub 2018 Dec 26. Neuropsychopharmacology. 2019. PMID: 30622300 Free PMC article.
51 results