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Recent Development of Visceral Leishmaniasis Treatments: Successes, Pitfalls, and Perspectives.
Alves F, Bilbe G, Blesson S, Goyal V, Monnerat S, Mowbray C, Muthoni Ouattara G, Pécoul B, Rijal S, Rode J, Solomos A, Strub-Wourgaft N, Wasunna M, Wells S, Zijlstra EE, Arana B, Alvar J. Alves F, et al. Among authors: mowbray c. Clin Microbiol Rev. 2018 Aug 29;31(4):e00048-18. doi: 10.1128/CMR.00048-18. Print 2018 Oct. Clin Microbiol Rev. 2018. PMID: 30158301 Free PMC article. Review.
Novel benzoxaborole, nitroimidazole and aminopyrazoles with activity against experimental cutaneous leishmaniasis.
Van Bocxlaer K, Caridha D, Black C, Vesely B, Leed S, Sciotti RJ, Wijnant GJ, Yardley V, Braillard S, Mowbray CE, Ioset JR, Croft SL. Van Bocxlaer K, et al. Among authors: mowbray ce. Int J Parasitol Drugs Drug Resist. 2019 Dec;11:129-138. doi: 10.1016/j.ijpddr.2019.02.002. Epub 2019 Feb 26. Int J Parasitol Drugs Drug Resist. 2019. PMID: 30922847 Free PMC article.
Route map for the discovery and pre-clinical development of new drugs and treatments for cutaneous leishmaniasis.
Caridha D, Vesely B, van Bocxlaer K, Arana B, Mowbray CE, Rafati S, Uliana S, Reguera R, Kreishman-Deitrick M, Sciotti R, Buffet P, Croft SL. Caridha D, et al. Int J Parasitol Drugs Drug Resist. 2019 Dec;11:106-117. doi: 10.1016/j.ijpddr.2019.06.003. Epub 2019 Jun 20. Int J Parasitol Drugs Drug Resist. 2019. PMID: 31320296 Free PMC article. Review.
2-aminobenzimidazoles for leishmaniasis: From initial hit discovery to in vivo profiling.
Ferreira RAA, Junior COR, Martinez PDG, Koovits PJ, Soares BM, Ferreira LLG, Michelan-Duarte S, Chelucci RC, Andricopulo AD, Galuppo MK, Uliana SRB, Matheeussen A, Caljon G, Maes L, Campbell S, Kratz JM, Mowbray CE, Dias LC. Ferreira RAA, et al. PLoS Negl Trop Dis. 2021 Feb 22;15(2):e0009196. doi: 10.1371/journal.pntd.0009196. eCollection 2021 Feb. PLoS Negl Trop Dis. 2021. PMID: 33617566 Free PMC article.
DNDI-6148: A Novel Benzoxaborole Preclinical Candidate for the Treatment of Visceral Leishmaniasis.
Mowbray CE, Braillard S, Glossop PA, Whitlock GA, Jacobs RT, Speake J, Pandi B, Nare B, Maes L, Yardley V, Freund Y, Wall RJ, Carvalho S, Bello D, Van den Kerkhof M, Caljon G, Gilbert IH, Corpas-Lopez V, Lukac I, Patterson S, Zuccotto F, Wyllie S. Mowbray CE, et al. J Med Chem. 2021 Nov 11;64(21):16159-16176. doi: 10.1021/acs.jmedchem.1c01437. Epub 2021 Oct 28. J Med Chem. 2021. PMID: 34711050 Free PMC article.
The Pandemic Response Box─Accelerating Drug Discovery Efforts after Disease Outbreaks.
Samby K, Besson D, Dutta A, Patra B, Doy A, Glossop P, Mills J, Whitlock G, Hooft van Huijsduijnen R, Monaco A, Bilbe G, Mowbray C, Perry B, Adam A, Wells TNC, Willis PA. Samby K, et al. Among authors: mowbray c. ACS Infect Dis. 2022 Apr 8;8(4):713-720. doi: 10.1021/acsinfecdis.1c00527. Epub 2022 Mar 14. ACS Infect Dis. 2022. PMID: 35286809 Free PMC article.
Novel Amino-pyrazole Ureas with Potent In Vitro and In Vivo Antileishmanial Activity.
Mowbray CE, Braillard S, Speed W, Glossop PA, Whitlock GA, Gibson KR, Mills JE, Brown AD, Gardner JM, Cao Y, Hua W, Morgans GL, Feijens PB, Matheeussen A, Maes LJ. Mowbray CE, et al. J Med Chem. 2015 Dec 24;58(24):9615-24. doi: 10.1021/acs.jmedchem.5b01456. Epub 2015 Dec 4. J Med Chem. 2015. PMID: 26571076 Free article.
In vitro and in vivo pharmacodynamics of three novel antileishmanial lead series.
Van den Kerkhof M, Mabille D, Chatelain E, Mowbray CE, Braillard S, Hendrickx S, Maes L, Caljon G. Van den Kerkhof M, et al. Among authors: mowbray ce. Int J Parasitol Drugs Drug Resist. 2018 Apr;8(1):81-86. doi: 10.1016/j.ijpddr.2018.01.006. Epub 2018 Jan 31. Int J Parasitol Drugs Drug Resist. 2018. PMID: 29425734 Free PMC article.
172 results