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Page 1
Detyrosinated microtubule arrays drive myofibrillar malformations in mdx muscle fibers.
Harriot AD, Altair Morris T, Vanegas C, Kallenbach J, Pinto K, Joca HC, Moutin MJ, Shi G, Ursitti JA, Grosberg A, Ward CW. Harriot AD, et al. Among authors: moutin mj. Front Cell Dev Biol. 2023 Aug 25;11:1209542. doi: 10.3389/fcell.2023.1209542. eCollection 2023. Front Cell Dev Biol. 2023. PMID: 37691825 Free PMC article.
VASH1-SVBP and VASH2-SVBP generate different detyrosination profiles on microtubules.
Ramirez-Rios S, Choi SR, Sanyal C, Blum TB, Bosc C, Krichen F, Denarier E, Soleilhac JM, Blot B, Janke C, Stoppin-Mellet V, Magiera MM, Arnal I, Steinmetz MO, Moutin MJ. Ramirez-Rios S, et al. Among authors: moutin mj. J Cell Biol. 2023 Feb 6;222(2):e202205096. doi: 10.1083/jcb.202205096. Epub 2022 Dec 13. J Cell Biol. 2023. PMID: 36512346 Free PMC article.
Crosstalk between acetylation and the tyrosination/detyrosination cycle of α-tubulin in Alzheimer's disease.
Martínez-Hernández J, Parato J, Sharma A, Soleilhac JM, Qu X, Tein E, Sproul A, Andrieux A, Goldberg Y, Moutin MJ, Bartolini F, Peris L. Martínez-Hernández J, et al. Among authors: moutin mj. Front Cell Dev Biol. 2022 Aug 26;10:926914. doi: 10.3389/fcell.2022.926914. eCollection 2022. Front Cell Dev Biol. 2022. PMID: 36092705 Free PMC article.
Posttranslational modification of microtubules by the MATCAP detyrosinase.
Landskron L, Bak J, Adamopoulos A, Kaplani K, Moraiti M, van den Hengel LG, Song JY, Bleijerveld OB, Nieuwenhuis J, Heidebrecht T, Henneman L, Moutin MJ, Barisic M, Taraviras S, Perrakis A, Brummelkamp TR. Landskron L, et al. Among authors: moutin mj. Science. 2022 May 20;376(6595):eabn6020. doi: 10.1126/science.abn6020. Epub 2022 May 20. Science. 2022. PMID: 35482892
Tubulin Carboxypeptidase Activity Promotes Focal Gelatin Degradation in Breast Tumor Cells and Induces Apoptosis in Breast Epithelial Cells That Is Overcome by Oncogenic Signaling.
Mathias TJ, Ju JA, Lee RM, Thompson KN, Mull ML, Annis DA, Chang KT, Ory EC, Stemberger MB, Hotta T, Ohi R, Vitolo MI, Moutin MJ, Martin SS. Mathias TJ, et al. Among authors: moutin mj. Cancers (Basel). 2022 Mar 28;14(7):1707. doi: 10.3390/cancers14071707. Cancers (Basel). 2022. PMID: 35406479 Free PMC article.
Tubulin tyrosination regulates synaptic function and is disrupted in Alzheimer's disease.
Peris L, Parato J, Qu X, Soleilhac JM, Lanté F, Kumar A, Pero ME, Martínez-Hernández J, Corrao C, Falivelli G, Payet F, Gory-Fauré S, Bosc C, Blanca Ramirez M, Sproul A, Brocard J, Di Cara B, Delagrange P, Buisson A, Goldberg Y, Moutin MJ, Bartolini F, Andrieux A. Peris L, et al. Among authors: moutin mj. Brain. 2022 Jul 29;145(7):2486-2506. doi: 10.1093/brain/awab436. Brain. 2022. PMID: 35148384 Free PMC article.
Oleoylethanolamide Delays the Dysfunction and Death of Purkinje Cells and Ameliorates Behavioral Defects in a Mouse Model of Cerebellar Neurodegeneration.
Pérez-Martín E, Muñoz-Castañeda R, Moutin MJ, Ávila-Zarza CA, Muñoz-Castañeda JM, Del Pilar C, Alonso JR, Andrieux A, Díaz D, Weruaga E. Pérez-Martín E, et al. Among authors: moutin mj. Neurotherapeutics. 2021 Jul;18(3):1748-1767. doi: 10.1007/s13311-021-01044-3. Epub 2021 Apr 7. Neurotherapeutics. 2021. PMID: 33829414 Free PMC article.
Proteomic and Functional Studies Reveal Detyrosinated Tubulin as Treatment Target in Sarcomere Mutation-Induced Hypertrophic Cardiomyopathy.
Schuldt M, Pei J, Harakalova M, Dorsch LM, Schlossarek S, Mokry M, Knol JC, Pham TV, Schelfhorst T, Piersma SR, Dos Remedios C, Dalinghaus M, Michels M, Asselbergs FW, Moutin MJ, Carrier L, Jimenez CR, van der Velden J, Kuster DWD. Schuldt M, et al. Among authors: moutin mj. Circ Heart Fail. 2021 Jan;14(1):e007022. doi: 10.1161/CIRCHEARTFAILURE.120.007022. Epub 2021 Jan 12. Circ Heart Fail. 2021. PMID: 33430602 Free PMC article.
48 results