Mouscadet JF - Search Results

1

Integrase and integration: biochemical activities of HIV-1 integrase.

Delelis O, Carayon K, Saïb A, Deprez E, Mouscadet JF. Delelis O, et al. Among authors: mouscadet jf. Retrovirology. 2008 Dec 17;5:114. doi: 10.1186/1742-4690-5-114. Retrovirology. 2008. PMID: 19091057 Free PMC article. Review.

2

A novel function for spumaretrovirus integrase: an early requirement for integrase-mediated cleavage of 2 LTR circles.

Delelis O, Petit C, Leh H, Mbemba G, Mouscadet JF, Sonigo P. Delelis O, et al. Among authors: mouscadet jf. Retrovirology. 2005 May 18;2:31. doi: 10.1186/1742-4690-2-31. Retrovirology. 2005. PMID: 15904533 Free PMC article.

3

Probing of HIV-1 integrase/DNA interactions using novel analogs of viral DNA.

Agapkina J, Smolov M, Barbe S, Zubin E, Zatsepin T, Deprez E, Le Bret M, Mouscadet JF, Gottikh M. Agapkina J, et al. Among authors: mouscadet jf. J Biol Chem. 2006 Apr 28;281(17):11530-40. doi: 10.1074/jbc.M512271200. Epub 2006 Feb 24. J Biol Chem. 2006. PMID: 16500899 Free article.

4

Relationship between the oligomeric status of HIV-1 integrase on DNA and enzymatic activity.

Guiot E, Carayon K, Delelis O, Simon F, Tauc P, Zubin E, Gottikh M, Mouscadet JF, Brochon JC, Deprez E. Guiot E, et al. Among authors: mouscadet jf. J Biol Chem. 2006 Aug 11;281(32):22707-19. doi: 10.1074/jbc.M602198200. Epub 2006 Jun 13. J Biol Chem. 2006. PMID: 16774912 Free article.

5

Efficient and specific internal cleavage of a retroviral palindromic DNA sequence by tetrameric HIV-1 integrase.

Delelis O, Parissi V, Leh H, Mbemba G, Petit C, Sonigo P, Deprez E, Mouscadet JF. Delelis O, et al. Among authors: mouscadet jf. PLoS One. 2007 Jul 11;2(7):e608. doi: 10.1371/journal.pone.0000608. PLoS One. 2007. PMID: 17622353 Free PMC article.

6

Insight into the integrase-DNA recognition mechanism. A specific DNA-binding mode revealed by an enzymatically labeled integrase.

Delelis O, Carayon K, Guiot E, Leh H, Tauc P, Brochon JC, Mouscadet JF, Deprez E. Delelis O, et al. Among authors: mouscadet jf. J Biol Chem. 2008 Oct 10;283(41):27838-27849. doi: 10.1074/jbc.M803257200. Epub 2008 Aug 12. J Biol Chem. 2008. PMID: 18697740 Free article.

7

Impact of Y143 HIV-1 integrase mutations on resistance to raltegravir in vitro and in vivo.

Delelis O, Thierry S, Subra F, Simon F, Malet I, Alloui C, Sayon S, Calvez V, Deprez E, Marcelin AG, Tchertanov L, Mouscadet JF. Delelis O, et al. Among authors: mouscadet jf. Antimicrob Agents Chemother. 2010 Jan;54(1):491-501. doi: 10.1128/AAC.01075-09. Epub 2009 Nov 9. Antimicrob Agents Chemother. 2010. PMID: 19901095 Free PMC article.

8

A cooperative and specific DNA-binding mode of HIV-1 integrase depends on the nature of the metallic cofactor and involves the zinc-containing N-terminal domain.

Carayon K, Leh H, Henry E, Simon F, Mouscadet JF, Deprez E. Carayon K, et al. Among authors: mouscadet jf. Nucleic Acids Res. 2010 Jun;38(11):3692-708. doi: 10.1093/nar/gkq087. Epub 2010 Feb 17. Nucleic Acids Res. 2010. PMID: 20164093 Free PMC article.

9

Resistance to HIV-1 integrase inhibitors: A structural perspective.

Mouscadet JF, Delelis O, Marcelin AG, Tchertanov L. Mouscadet JF, et al. Drug Resist Updat. 2010 Aug-Oct;13(4-5):139-50. doi: 10.1016/j.drup.2010.05.001. Epub 2010 Jun 8. Drug Resist Updat. 2010. PMID: 20570551 Review.

10

G140S/Q148R and N155H mutations render HIV-2 Integrase resistant to raltegravir whereas Y143C does not.

Ni XJ, Delelis O, Charpentier C, Storto A, Collin G, Damond F, Descamps D, Mouscadet JF. Ni XJ, et al. Among authors: mouscadet jf. Retrovirology. 2011 Aug 19;8:68. doi: 10.1186/1742-4690-8-68. Retrovirology. 2011. PMID: 21854605 Free PMC article.

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