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IMI2-PainCare-BioPain-RCT2 protocol: a randomized, double-blind, placebo-controlled, crossover, multicenter trial in healthy subjects to investigate the effects of lacosamide, pregabalin, and tapentadol on biomarkers of pain processing observed by non-invasive neurophysiological measurements of human spinal cord and brainstem activity.
Leone C, Di Stefano G, Di Pietro G, Bloms-Funke P, Boesl I, Caspani O, Chapman SC, Finnerup NB, Garcia-Larrea L, Li T, Goetz M, Mouraux A, Pelz B, Pogatzki-Zahn E, Schilder A, Schnetter E, Schubart K, Tracey I, Troconiz IF, Van Niel H, Hernandez JMV, Vincent K, Vollert J, Wanigasekera V, Wittayer M, Phillips KG, Truini A, Treede RD. Leone C, et al. Among authors: mouraux a. Trials. 2022 Sep 5;23(1):739. doi: 10.1186/s13063-022-06431-5. Trials. 2022. PMID: 36064434 Free PMC article.
Human surrogate models of central sensitization: A critical review and practical guide.
Quesada C, Kostenko A, Ho I, Leone C, Nochi Z, Stouffs A, Wittayer M, Caspani O, Brix Finnerup N, Mouraux A, Pickering G, Tracey I, Truini A, Treede RD, Garcia-Larrea L. Quesada C, et al. Among authors: mouraux a. Eur J Pain. 2021 Aug;25(7):1389-1428. doi: 10.1002/ejp.1768. Epub 2021 May 8. Eur J Pain. 2021. PMID: 33759294 Free PMC article. Review.
IMI2-PainCare-BioPain-RCT3: a randomized, double-blind, placebo-controlled, crossover, multi-center trial in healthy subjects to investigate the effects of lacosamide, pregabalin, and tapentadol on biomarkers of pain processing observed by electroencephalography (EEG).
Mouraux A, Bloms-Funke P, Boesl I, Caspani O, Chapman SC, Di Stefano G, Finnerup NB, Garcia-Larrea L, Goetz M, Kostenko A, Pelz B, Pogatzki-Zahn E, Schubart K, Stouffs A, Truini A, Tracey I, Troconiz IF, Van Niel J, Vela JM, Vincent K, Vollert J, Wanigasekera V, Wittayer M, Phillips KG, Treede RD. Mouraux A, et al. Trials. 2021 Jun 17;22(1):404. doi: 10.1186/s13063-021-05272-y. Trials. 2021. PMID: 34140041 Free PMC article. Clinical Trial.
Modulation of the N13 component of the somatosensory evoked potentials in an experimental model of central sensitization in humans.
Di Lionardo A, Di Stefano G, Leone C, Di Pietro G, Sgro E, Malara E, Cosentino C, Mollica C, Blockeel AJ, Caspani O, Garcia-Larrea L, Mouraux A, Treede RD, Phillips KG, Valeriani M, Truini A. Di Lionardo A, et al. Among authors: mouraux a. Sci Rep. 2021 Oct 21;11(1):20838. doi: 10.1038/s41598-021-00313-7. Sci Rep. 2021. PMID: 34675309 Free PMC article.
The N13 spinal component of somatosensory evoked potentials is modulated by heterotopic noxious conditioning stimulation suggesting an involvement of spinal wide dynamic range neurons.
Pietro GD, Stefano GD, Leone C, Lionardo AD, Sgrò E, Blockeel AJ, Caspani O, Garcia-Larrea L, Mouraux A, Phillips KG, Treede RD, Valeriani M, Truini A. Pietro GD, et al. Among authors: mouraux a. Neurophysiol Clin. 2021 Dec;51(6):517-523. doi: 10.1016/j.neucli.2021.09.001. Epub 2021 Oct 28. Neurophysiol Clin. 2021. PMID: 34756635 Free article.
IMI2-PainCare-BioPain-RCT1: study protocol for a randomized, double-blind, placebo-controlled, crossover, multi-center trial in healthy subjects to investigate the effects of lacosamide, pregabalin, and tapentadol on biomarkers of pain processing observed by peripheral nerve excitability testing (NET).
Nochi Z, Pia H, Bloms-Funke P, Boesl I, Caspani O, Chapman SC, Fardo F, Genser B, Goetz M, Kostenko AV, Leone C, Li T, Mouraux A, Pelz B, Pogatzki-Zahn E, Schilder A, Schnetter E, Schubart K, Stouffs A, Tracey I, Troconiz IF, Truini A, Van Niel J, Vela JM, Vincent K, Vollert J, Wanigasekera V, Wittayer M, Tankisi H, Finnerup NB, Phillips KG, Treede RD. Nochi Z, et al. Among authors: mouraux a. Trials. 2022 Feb 19;23(1):163. doi: 10.1186/s13063-022-06087-1. Trials. 2022. PMID: 35183242 Free PMC article.
188 results