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Deguelin exerts potent nematocidal activity via the mitochondrial respiratory chain.
Preston S, Korhonen PK, Mouchiroud L, Cornaglia M, McGee SL, Young ND, Davis RA, Crawford S, Nowell C, Ansell BRE, Fisher GM, Andrews KT, Chang BCH, Gijs MAM, Sternberg PW, Auwerx J, Baell J, Hofmann A, Jabbar A, Gasser RB. Preston S, et al. Among authors: mouchiroud l. FASEB J. 2017 Oct;31(10):4515-4532. doi: 10.1096/fj.201700288R. Epub 2017 Jul 7. FASEB J. 2017. PMID: 28687609
This study highlights the dynamic biologic response of multicellular organisms to deguelin perturbation.-Preston, S., Korhonen, P. K., Mouchiroud, L., Cornaglia, M., McGee, S. L., Young, N. D., Davis, R. ...
This study highlights the dynamic biologic response of multicellular organisms to deguelin perturbation.-Preston, S., Korhonen, P. K., Mo …
Mitonuclear protein imbalance as a conserved longevity mechanism.
Houtkooper RH, Mouchiroud L, Ryu D, Moullan N, Katsyuba E, Knott G, Williams RW, Auwerx J. Houtkooper RH, et al. Among authors: mouchiroud l. Nature. 2013 May 23;497(7450):451-7. doi: 10.1038/nature12188. Nature. 2013. PMID: 23698443 Free PMC article.
Transcriptional coregulators: fine-tuning metabolism.
Mouchiroud L, Eichner LJ, Shaw RJ, Auwerx J. Mouchiroud L, et al. Cell Metab. 2014 Jul 1;20(1):26-40. doi: 10.1016/j.cmet.2014.03.027. Epub 2014 May 1. Cell Metab. 2014. PMID: 24794975 Free PMC article. Review.
Pharmacological Inhibition of poly(ADP-ribose) polymerases improves fitness and mitochondrial function in skeletal muscle.
Pirinen E, Cantó C, Jo YS, Morato L, Zhang H, Menzies KJ, Williams EG, Mouchiroud L, Moullan N, Hagberg C, Li W, Timmers S, Imhof R, Verbeek J, Pujol A, van Loon B, Viscomi C, Zeviani M, Schrauwen P, Sauve AA, Schoonjans K, Auwerx J. Pirinen E, et al. Among authors: mouchiroud l. Cell Metab. 2014 Jun 3;19(6):1034-41. doi: 10.1016/j.cmet.2014.04.002. Epub 2014 May 8. Cell Metab. 2014. PMID: 24814482 Free PMC article.
39 results