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Interactions between 4-aminoquinoline and heme: Promising mechanism against Trypanosoma cruzi.
Lechuga GC, Borges JC, Calvet CM, de Araújo HP, Zuma AA, do Nascimento SB, Motta MCM, Bernardino AMR, Pereira MCS, Bourguignon SC. Lechuga GC, et al. Among authors: motta mcm. Int J Parasitol Drugs Drug Resist. 2016 Dec;6(3):154-164. doi: 10.1016/j.ijpddr.2016.07.001. Epub 2016 Jul 14. Int J Parasitol Drugs Drug Resist. 2016. PMID: 27490082 Free PMC article.
Unveiling benznidazole's mechanism of action through overexpression of DNA repair proteins in Trypanosoma cruzi.
Rajão MA, Furtado C, Alves CL, Passos-Silva DG, de Moura MB, Schamber-Reis BL, Kunrath-Lima M, Zuma AA, Vieira-da-Rocha JP, Garcia JB, Mendes IC, Pena SD, Macedo AM, Franco GR, de Souza-Pinto NC, de Medeiros MH, Cruz AK, Motta MC, Teixeira SM, Machado CR. Rajão MA, et al. Environ Mol Mutagen. 2014 May;55(4):309-21. doi: 10.1002/em.21839. Epub 2013 Dec 18. Environ Mol Mutagen. 2014. PMID: 24347026
DNA polymerase beta from Trypanosoma cruzi is involved in kinetoplast DNA replication and repair of oxidative lesions.
Schamber-Reis BL, Nardelli S, Régis-Silva CG, Campos PC, Cerqueira PG, Lima SA, Franco GR, Macedo AM, Pena SD, Cazaux C, Hoffmann JS, Motta MC, Schenkman S, Teixeira SM, Machado CR. Schamber-Reis BL, et al. Mol Biochem Parasitol. 2012 Jun;183(2):122-31. doi: 10.1016/j.molbiopara.2012.02.007. Epub 2012 Feb 24. Mol Biochem Parasitol. 2012. PMID: 22369885 Free article.
Open chromatin analysis in Trypanosoma cruzi life forms highlights critical differences in genomic compartments and developmental regulation at tDNA loci.
Lima ARJ, Silva HGS, Poubel S, Rosón JN, de Lima LPO, Costa-Silva HM, Gonçalves CS, Galante PAF, Holetz F, Motta MCM, Silber AM, Elias MC, da Cunha JPC. Lima ARJ, et al. Among authors: motta mcm. Epigenetics Chromatin. 2022 Jun 1;15(1):22. doi: 10.1186/s13072-022-00450-x. Epigenetics Chromatin. 2022. PMID: 35650626 Free PMC article.
67 results