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Epigenomic and transcriptional profiling identifies impaired glyoxylate detoxification in NAFLD as a risk factor for hyperoxaluria.
Gianmoena K, Gasparoni N, Jashari A, Gabrys P, Grgas K, Ghallab A, Nordström K, Gasparoni G, Reinders J, Edlund K, Godoy P, Schriewer A, Hayen H, Hudert CA, Damm G, Seehofer D, Weiss TS, Boor P, Anders HJ, Motrapu M, Jansen P, Schiergens TS, Falk-Paulsen M, Rosenstiel P, Lisowski C, Salido E, Marchan R, Walter J, Hengstler JG, Cadenas C. Gianmoena K, et al. Among authors: motrapu m. Cell Rep. 2021 Aug 24;36(8):109526. doi: 10.1016/j.celrep.2021.109526. Cell Rep. 2021. PMID: 34433051 Free article.
No NLRP3 inflammasome activity in kidney epithelial cells, not even when the NLRP3-A350V Muckle-Wells variant is expressed in podocytes of diabetic mice.
Kunte SC, Marschner JA, Klaus M, Honda T, Li C, Motrapu M, Walz C, Angelotti ML, Antonelli G, Melica ME, De Chiara L, Semeraro R, Nelson PJ, Anders HJ. Kunte SC, et al. Among authors: motrapu m. Front Immunol. 2023 Aug 23;14:1230050. doi: 10.3389/fimmu.2023.1230050. eCollection 2023. Front Immunol. 2023. PMID: 37744356 Free PMC article.
Tubular Epithelial Cell HMGB1 Promotes AKI-CKD Transition by Sensitizing Cycling Tubular Cells to Oxidative Stress: A Rationale for Targeting HMGB1 during AKI Recovery.
Zhao ZB, Marschner JA, Iwakura T, Li C, Motrapu M, Kuang M, Popper B, Linkermann A, Klocke J, Enghard P, Muto Y, Humphreys BD, Harris HE, Romagnani P, Anders HJ. Zhao ZB, et al. Among authors: motrapu m. J Am Soc Nephrol. 2023 Mar 1;34(3):394-411. doi: 10.1681/ASN.0000000000000024. Epub 2023 Jan 17. J Am Soc Nephrol. 2023. PMID: 36857499 Free PMC article.
11 results