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Validation of the multiple sensor mechanism of the Keap1-Nrf2 system.
Takaya K, Suzuki T, Motohashi H, Onodera K, Satomi S, Kensler TW, Yamamoto M. Takaya K, et al. Among authors: motohashi h. Free Radic Biol Med. 2012 Aug 15;53(4):817-27. doi: 10.1016/j.freeradbiomed.2012.06.023. Epub 2012 Jun 23. Free Radic Biol Med. 2012. PMID: 22732183 Free PMC article.
Hydrogen sulfide anion regulates redox signaling via electrophile sulfhydration.
Nishida M, Sawa T, Kitajima N, Ono K, Inoue H, Ihara H, Motohashi H, Yamamoto M, Suematsu M, Kurose H, van der Vliet A, Freeman BA, Shibata T, Uchida K, Kumagai Y, Akaike T. Nishida M, et al. Among authors: motohashi h. Nat Chem Biol. 2012 Aug;8(8):714-24. doi: 10.1038/nchembio.1018. Epub 2012 Jul 1. Nat Chem Biol. 2012. PMID: 22772154 Free PMC article.
Keap1 degradation by autophagy for the maintenance of redox homeostasis.
Taguchi K, Fujikawa N, Komatsu M, Ishii T, Unno M, Akaike T, Motohashi H, Yamamoto M. Taguchi K, et al. Among authors: motohashi h. Proc Natl Acad Sci U S A. 2012 Aug 21;109(34):13561-6. doi: 10.1073/pnas.1121572109. Epub 2012 Aug 7. Proc Natl Acad Sci U S A. 2012. PMID: 22872865 Free PMC article.
Reactive cysteine persulfides and S-polythiolation regulate oxidative stress and redox signaling.
Ida T, Sawa T, Ihara H, Tsuchiya Y, Watanabe Y, Kumagai Y, Suematsu M, Motohashi H, Fujii S, Matsunaga T, Yamamoto M, Ono K, Devarie-Baez NO, Xian M, Fukuto JM, Akaike T. Ida T, et al. Among authors: motohashi h. Proc Natl Acad Sci U S A. 2014 May 27;111(21):7606-11. doi: 10.1073/pnas.1321232111. Epub 2014 Apr 14. Proc Natl Acad Sci U S A. 2014. PMID: 24733942 Free PMC article.
Roles of Nrf2 in cell proliferation and differentiation.
Murakami S, Motohashi H. Murakami S, et al. Among authors: motohashi h. Free Radic Biol Med. 2015 Nov;88(Pt B):168-178. doi: 10.1016/j.freeradbiomed.2015.06.030. Epub 2015 Jun 25. Free Radic Biol Med. 2015. PMID: 26119783 Review.
Redox signaling regulated by electrophiles and reactive sulfur species.
Nishida M, Kumagai Y, Ihara H, Fujii S, Motohashi H, Akaike T. Nishida M, et al. Among authors: motohashi h. J Clin Biochem Nutr. 2016 Mar;58(2):91-8. doi: 10.3164/jcbn.15-111. Epub 2016 Feb 17. J Clin Biochem Nutr. 2016. PMID: 27013774 Free PMC article. Review.
319 results