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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1919 1
1920 1
1947 1
1949 1
1950 1
1951 1
1952 3
1953 2
1954 4
1955 1
1956 2
1957 7
1958 2
1959 7
1960 7
1961 10
1962 10
1963 25
1964 20
1965 15
1966 1
1967 2
1968 2
1969 4
1970 1
1971 5
1972 5
1973 7
1974 14
1975 29
1976 39
1977 45
1978 48
1979 80
1980 120
1981 136
1982 169
1983 303
1984 365
1985 474
1986 589
1987 861
1988 1144
1989 1587
1990 2136
1991 2776
1992 3489
1993 4238
1994 5267
1995 5866
1996 6246
1997 6877
1998 7653
1999 8509
2000 9456
2001 9898
2002 9953
2003 10318
2004 11298
2005 11247
2006 11901
2007 12005
2008 12685
2009 13716
2010 14529
2011 15327
2012 16318
2013 16289
2014 16028
2015 16066
2016 17195
2017 17860
2018 17651
2019 17840
2020 18546
2021 18558
2022 15010
2023 14338
2024 5650

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374,732 results

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Page 1
Showing results for motif i
Search for Motiul I instead (1 results)
ZBP1: Innate Sensor Regulating Cell Death and Inflammation.
Kuriakose T, Kanneganti TD. Kuriakose T, et al. Trends Immunol. 2018 Feb;39(2):123-134. doi: 10.1016/j.it.2017.11.002. Epub 2017 Nov 25. Trends Immunol. 2018. PMID: 29236673 Free PMC article. Review.
Z-DNA-binding protein 1 (ZBP1), initially reported as an interferon (IFN)-inducible tumor-associated protein, harbors nucleic acid-binding domains for left-handed helix (Z-form) and receptor-interacting protein homotypic interaction motif (RHIM) …
Z-DNA-binding protein 1 (ZBP1), initially reported as an interferon (IFN)-inducible tumor-associated protein, harbors nucleic …
N-degron and C-degron pathways of protein degradation.
Varshavsky A. Varshavsky A. Proc Natl Acad Sci U S A. 2019 Jan 8;116(2):358-366. doi: 10.1073/pnas.1816596116. Proc Natl Acad Sci U S A. 2019. PMID: 30622213 Free PMC article. Review.
N-degrons and C-degrons include, to varying extents, adjoining sequence motifs, and also internal lysine residues that function as polyubiquitylation sites. ...
N-degrons and C-degrons include, to varying extents, adjoining sequence motifs, and also internal lysine residues that function as po …
Phase Separation and Neurodegenerative Diseases: A Disturbance in the Force.
Zbinden A, Pérez-Berlanga M, De Rossi P, Polymenidou M. Zbinden A, et al. Dev Cell. 2020 Oct 12;55(1):45-68. doi: 10.1016/j.devcel.2020.09.014. Dev Cell. 2020. PMID: 33049211 Free article. Review.
Protein aggregation is the main hallmark of neurodegenerative diseases. ...Emerging evidence supports the hypothesis that aberrant phase separation behavior may serve as a trigger of protein aggregation in neurodegeneration, and efforts to understand and control the …
Protein aggregation is the main hallmark of neurodegenerative diseases. ...Emerging evidence supports the hypothesis that aberrant ph …
Affinity and specificity of motif-based protein-protein interactions.
Ivarsson Y, Jemth P. Ivarsson Y, et al. Curr Opin Struct Biol. 2019 Feb;54:26-33. doi: 10.1016/j.sbi.2018.09.009. Epub 2018 Oct 24. Curr Opin Struct Biol. 2019. PMID: 30368054 Review.
It is becoming increasingly clear that eukaryotic cell physiology is largely controlled by protein-protein interactions involving disordered protein regions, which usually interact with globular domains in a coupled binding and folding reaction. Severa …
It is becoming increasingly clear that eukaryotic cell physiology is largely controlled by protein-protein interactions involv …
Protein-coding tRNA sequences?
Jimenez J. Jimenez J. Gene. 2022 Mar 10;814:146154. doi: 10.1016/j.gene.2021.146154. Epub 2022 Jan 4. Gene. 2022. PMID: 34995735
These extremely conserved RNA molecules transfer amino acids to the ribosome for the synthesis of proteins encoded by mRNAs, but canonical tRNAs are not protein-coding RNAs. Surprisely, when virtually translated, I observed that peptides derived from tRNA sequences match t …
These extremely conserved RNA molecules transfer amino acids to the ribosome for the synthesis of proteins encoded by mRNAs, but canonical t …
Emerging Features of Linear Motif-Binding Hub Proteins.
Jespersen N, Barbar E. Jespersen N, et al. Trends Biochem Sci. 2020 May;45(5):375-384. doi: 10.1016/j.tibs.2020.01.004. Epub 2020 Feb 20. Trends Biochem Sci. 2020. PMID: 32311332 Review.
Static hubs interact with their partners simultaneously, while dynamic hubs bind different partners at different locations and times. Although this distinguishes some features of hub protein/partner interactions, the increasing literature requires an expanded categorizatio …
Static hubs interact with their partners simultaneously, while dynamic hubs bind different partners at different locations and times. Althou …
Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.
Mihalič F, Benz C, Kassa E, Lindqvist R, Simonetti L, Inturi R, Aronsson H, Andersson E, Chi CN, Davey NE, Överby AK, Jemth P, Ivarsson Y. Mihalič F, et al. Nat Commun. 2023 Sep 13;14(1):5636. doi: 10.1038/s41467-023-41312-8. Nat Commun. 2023. PMID: 37704626 Free PMC article.
The virus life cycle depends on host-virus protein-protein interactions, which often involve a disordered protein region binding to a folded protein domain. Here, we used proteomic peptide phage display (ProP-PD) to identify peptides from the intrinsic …
The virus life cycle depends on host-virus protein-protein interactions, which often involve a disordered protein regio …
Allostery Frustrates the Experimentalist.
Gianni S, Jemth P. Gianni S, et al. J Mol Biol. 2023 Feb 28;435(4):167934. doi: 10.1016/j.jmb.2022.167934. Epub 2022 Dec 28. J Mol Biol. 2023. PMID: 36586463 Free article. Review.
Over the last decades the concept of allostery was broadened to embrace all types of long-range interactions across a protein including purely entropic changes without a conformational change in single protein domains. ...We arrive at the conclusion that the …
Over the last decades the concept of allostery was broadened to embrace all types of long-range interactions across a protein includi …
ELM-the eukaryotic linear motif resource in 2020.
Kumar M, Gouw M, Michael S, Sámano-Sánchez H, Pancsa R, Glavina J, Diakogianni A, Valverde JA, Bukirova D, Čalyševa J, Palopoli N, Davey NE, Chemes LB, Gibson TJ. Kumar M, et al. Nucleic Acids Res. 2020 Jan 8;48(D1):D296-D306. doi: 10.1093/nar/gkz1030. Nucleic Acids Res. 2020. PMID: 31680160 Free PMC article.
The eukaryotic linear motif (ELM) resource is a repository of manually curated experimentally validated short linear motifs (SLiMs). ...The current release of the ELM database contains 289 motif classes and 3523 individual protein motif instance …
The eukaryotic linear motif (ELM) resource is a repository of manually curated experimentally validated short linear motifs (S …
Tripartite motif-containing proteins precisely and positively affect host antiviral immune response.
Wei Y, Chen S, Wang M, Cheng A. Wei Y, et al. Scand J Immunol. 2018 Jun;87(6):e12669. doi: 10.1111/sji.12669. Scand J Immunol. 2018. PMID: 29706026 Free article. Review.
The tripartite motif-containing proteins (TRIMs) comprise a large family of proteins with over 70 members in humans. ...
The tripartite motif-containing proteins (TRIMs) comprise a large family of proteins with over 70 members in humans. ...
374,732 results
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