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Benznidazole, the trypanocidal drug used for Chagas disease, induces hepatic NRF2 activation and attenuates the inflammatory response in a murine model of sepsis.
Lambertucci F, Motiño O, Villar S, Rigalli JP, de Luján Alvarez M, Catania VA, Martín-Sanz P, Carnovale CE, Quiroga AD, Francés DE, Ronco MT. Lambertucci F, et al. Among authors: motino o. Toxicol Appl Pharmacol. 2017 Jan 15;315:12-22. doi: 10.1016/j.taap.2016.11.015. Epub 2016 Nov 27. Toxicol Appl Pharmacol. 2017. PMID: 27899278
PGE2 induces apoptosis of hepatic stellate cells and attenuates liver fibrosis in mice by downregulating miR-23a-5p and miR-28a-5p.
Brea R, Motiño O, Francés D, García-Monzón C, Vargas J, Fernández-Velasco M, Boscá L, Casado M, Martín-Sanz P, Agra N. Brea R, et al. Among authors: motino o. Biochim Biophys Acta Mol Basis Dis. 2018 Feb;1864(2):325-337. doi: 10.1016/j.bbadis.2017.11.001. Epub 2017 Nov 3. Biochim Biophys Acta Mol Basis Dis. 2018. PMID: 29109031 Free article.
Effects of acyl-coenzyme A binding protein (ACBP)/diazepam-binding inhibitor (DBI) on body mass index.
Joseph A, Chen H, Anagnostopoulos G, Montégut L, Lafarge A, Motiño O, Castedo M, Maiuri MC, Clément K, Terrisse S, Martin AL, Vaz-Luis I, Andre F, Grundler F, de Toledo FW, Madeo F, Zitvogel L, Goldwasser F, Blanchet B, Fumeron F, Roussel R, Martins I, Kroemer G. Joseph A, et al. Among authors: motino o. Cell Death Dis. 2021 Jun 9;12(6):599. doi: 10.1038/s41419-021-03864-9. Cell Death Dis. 2021. PMID: 34108446 Free PMC article.
Paradoxical implication of BAX/BAK in the persistence of tetraploid cells.
Deng J, Gutiérrez LG, Stoll G, Motiño O, Martins I, Núñez L, Bravo-San Pedro JM, Humeau J, Bordenave C, Pan J, Fohrer-Ting H, Souquere S, Pierron G, Hetz C, Villalobos C, Kroemer G, Senovilla L. Deng J, et al. Among authors: motino o. Cell Death Dis. 2021 Nov 1;12(11):1039. doi: 10.1038/s41419-021-04321-3. Cell Death Dis. 2021. PMID: 34725331 Free PMC article.
33 results