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S100A1: a regulator of myocardial contractility.
Most P, Bernotat J, Ehlermann P, Pleger ST, Reppel M, Börries M, Niroomand F, Pieske B, Janssen PM, Eschenhagen T, Karczewski P, Smith GL, Koch WJ, Katus HA, Remppis A. Most P, et al. Proc Natl Acad Sci U S A. 2001 Nov 20;98(24):13889-94. doi: 10.1073/pnas.241393598. Proc Natl Acad Sci U S A. 2001. PMID: 11717446 Free PMC article.
The C terminus (amino acids 75-94) and the linker region (amino acids 42-54) of the Ca2+-binding protein S100A1 differentially enhance sarcoplasmic Ca2+ release in murine skinned skeletal muscle fibers.
Most P, Remppis A, Weber C, Bernotat J, Ehlermann P, Pleger ST, Kirsch W, Weber M, Uttenweiler D, Smith GL, Katus HA, Fink RH. Most P, et al. J Biol Chem. 2003 Jul 18;278(29):26356-64. doi: 10.1074/jbc.M303338200. Epub 2003 Apr 28. J Biol Chem. 2003. PMID: 12721284 Free article.
Transgenic overexpression of the Ca2+-binding protein S100A1 in the heart leads to increased in vivo myocardial contractile performance.
Most P, Remppis A, Pleger ST, Löffler E, Ehlermann P, Bernotat J, Kleuss C, Heierhorst J, Ruiz P, Witt H, Karczewski P, Mao L, Rockman HA, Duncan SJ, Katus HA, Koch WJ. Most P, et al. J Biol Chem. 2003 Sep 5;278(36):33809-17. doi: 10.1074/jbc.M301788200. Epub 2003 May 30. J Biol Chem. 2003. PMID: 12777394 Free article.
S100A1 gene transfer: a strategy to strengthen engineered cardiac grafts.
Remppis A, Pleger ST, Most P, Lindenkamp J, Ehlermann P, Schweda C, Löffler E, Weichenhan D, Zimmermann W, Eschenhagen T, Koch WJ, Katus HA. Remppis A, et al. Among authors: most p. J Gene Med. 2004 Apr;6(4):387-94. doi: 10.1002/jgm.513. J Gene Med. 2004. PMID: 15079813
Hope for a broken heart?
Most P, Eicher C, Völkers M, Pleger ST, Katus HA. Most P, et al. Trends Biotechnol. 2004 Oct;22(10):487-9. doi: 10.1016/j.tibtech.2004.08.004. Trends Biotechnol. 2004. PMID: 15450736
212 results