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Chagasic thymic atrophy does not affect negative selection but results in the export of activated CD4+CD8+ T cells in severe forms of human disease.
Morrot A, Terra-Granado E, Pérez AR, Silva-Barbosa SD, Milićević NM, Farias-de-Oliveira DA, Berbert LR, De Meis J, Takiya CM, Beloscar J, Wang X, Kont V, Peterson P, Bottasso O, Savino W. Morrot A, et al. PLoS Negl Trop Dis. 2011 Aug;5(8):e1268. doi: 10.1371/journal.pntd.0001268. Epub 2011 Aug 16. PLoS Negl Trop Dis. 2011. PMID: 21858238 Free PMC article.
Trans-sialidase from Trypanosoma cruzi enhances the adhesion properties and fibronectin-driven migration of thymocytes.
Nardy AF, Luiz da Silva Filho J, Pérez AR, de Meis J, Farias-de-Oliveira DA, Penha L, de Araújo Oliveira I, Dias WB, Todeschini AR, Freire-de-Lima CG, Bellio M, Caruso-Neves C, Pinheiro AA, Takiya CM, Bottasso O, Savino W, Morrot A. Nardy AF, et al. Among authors: morrot a. Microbes Infect. 2013 May;15(5):365-74. doi: 10.1016/j.micinf.2013.02.003. Epub 2013 Feb 24. Microbes Infect. 2013. PMID: 23481510 Free article.
Inhibitory effects of Trypanosoma cruzi sialoglycoproteins on CD4+ T cells are associated with increased susceptibility to infection.
Nunes MP, Fortes B, Silva-Filho JL, Terra-Granado E, Santos L, Conde L, de Araújo Oliveira I, Freire-de-Lima L, Martins MV, Pinheiro AA, Takyia CM, Freire-de-Lima CG, Todeschini AR, Dosreis GA, Morrot A. Nunes MP, et al. Among authors: morrot a. PLoS One. 2013 Oct 28;8(10):e77568. doi: 10.1371/journal.pone.0077568. eCollection 2013. PLoS One. 2013. PMID: 24204874 Free PMC article.
Neutrophils increase or reduce parasite burden in Trypanosoma cruzi-infected macrophages, depending on host strain: role of neutrophil elastase.
Luna-Gomes T, Filardy AA, Rocha JD, Decote-Ricardo D, LaRocque-de-Freitas IF, Morrot A, Bozza PT, Castro-Faria-Neto HC, DosReis GA, Nunes MP, Freire-de-Lima CG. Luna-Gomes T, et al. Among authors: morrot a. PLoS One. 2014 Mar 5;9(3):e90582. doi: 10.1371/journal.pone.0090582. eCollection 2014. PLoS One. 2014. PMID: 24599360 Free PMC article.
Early double-negative thymocyte export in Trypanosoma cruzi infection is restricted by sphingosine receptors and associated with human chagas disease.
Lepletier A, de Almeida L, Santos L, da Silva Sampaio L, Paredes B, González FB, Freire-de-Lima CG, Beloscar J, Bottasso O, Einicker-Lamas M, Pérez AR, Savino W, Morrot A. Lepletier A, et al. Among authors: morrot a. PLoS Negl Trop Dis. 2014 Oct 16;8(10):e3203. doi: 10.1371/journal.pntd.0003203. eCollection 2014 Oct. PLoS Negl Trop Dis. 2014. PMID: 25330249 Free PMC article.
126 results