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Telomeric injury by KML001 in human T cells induces mitochondrial dysfunction through the p53-PGC-1α pathway.
Schank M, Zhao J, Wang L, Li Z, Cao D, Nguyen LN, Dang X, Khanal S, Nguyen LNT, Thakuri BKC, Ogbu SC, Lu Z, Zhang J, Wu XY, Morrison ZD, El Gazzar M, Ning S, Moorman JP, Yao ZQ. Schank M, et al. Among authors: morrison zd. Cell Death Dis. 2020 Dec 2;11(12):1030. doi: 10.1038/s41419-020-03238-7. Cell Death Dis. 2020. PMID: 33268822 Free PMC article.
Disruption of Telomere Integrity and DNA Repair Machineries by KML001 Induces T Cell Senescence, Apoptosis, and Cellular Dysfunctions.
Cao D, Zhao J, Nguyan LN, Nguyen LNT, Khanal S, Dang X, Schank M, Chand Thakuri BK, Wu XY, Morrison ZD, El Gazzar M, Zou Y, Ning S, Wang L, Moorman JP, Yao ZQ. Cao D, et al. Among authors: morrison zd. Front Immunol. 2019 May 22;10:1152. doi: 10.3389/fimmu.2019.01152. eCollection 2019. Front Immunol. 2019. PMID: 31191531 Free PMC article.
Inhibition of topoisomerase IIA (Top2α) induces telomeric DNA damage and T cell dysfunction during chronic viral infection.
Dang X, Ogbu SC, Zhao J, Nguyen LNT, Cao D, Nguyen LN, Khanal S, Schank M, Thakuri BKC, Wu XY, Morrison ZD, Zhang J, Li Z, El Gazzar M, Ning S, Wang L, Wang Z, Moorman JP, Yao ZQ. Dang X, et al. Among authors: morrison zd. Cell Death Dis. 2020 Mar 19;11(3):196. doi: 10.1038/s41419-020-2395-2. Cell Death Dis. 2020. PMID: 32193368 Free PMC article.
Telomere and ATM Dynamics in CD4 T-Cell Depletion in Active and Virus-Suppressed HIV Infections.
Khanal S, Tang Q, Cao D, Zhao J, Nguyen LN, Oyedeji OS, Dang X, Nguyen LNT, Schank M, Thakuri BKC, Ogbu C, Morrison ZD, Wu XY, Zhang Z, He Q, El Gazzar M, Li Z, Ning S, Wang L, Moorman JP, Yao ZQ. Khanal S, et al. Among authors: morrison zd. J Virol. 2020 Oct 27;94(22):e01061-20. doi: 10.1128/JVI.01061-20. Print 2020 Oct 27. J Virol. 2020. PMID: 32907975 Free PMC article.
Long Non-coding RNA GAS5 Regulates T Cell Functions via miR21-Mediated Signaling in People Living With HIV.
Nguyen LNT, Nguyen LN, Zhao J, Schank M, Dang X, Cao D, Khanal S, Chand Thakuri BK, Lu Z, Zhang J, Li Z, Morrison ZD, Wu XY, El Gazzar M, Ning S, Wang L, Moorman JP, Yao ZQ. Nguyen LNT, et al. Among authors: morrison zd. Front Immunol. 2021 Mar 12;12:601298. doi: 10.3389/fimmu.2021.601298. eCollection 2021. Front Immunol. 2021. PMID: 33776993 Free PMC article.
Mitochondrial Functions Are Compromised in CD4 T Cells From ART-Controlled PLHIV.
Zhao J, Schank M, Wang L, Li Z, Nguyen LN, Dang X, Cao D, Khanal S, Nguyen LNT, Thakuri BKC, Ogbu SC, Lu Z, Wu XY, Morrison ZD, Gazzar ME, Liu Y, Zhang J, Ning S, Moorman JP, Yao ZQ. Zhao J, et al. Among authors: morrison zd. Front Immunol. 2021 May 4;12:658420. doi: 10.3389/fimmu.2021.658420. eCollection 2021. Front Immunol. 2021. PMID: 34017335 Free PMC article.
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