Vitamin A regulates Akt signaling through the phospholipid fatty acid composition.
Pein H, Koeberle SC, Voelkel M, Schneider F, Rossi A, Thürmer M, Loeser K, Sautebin L, Morrison H, Werz O, Koeberle A.
Pein H, et al. Among authors: morrison h.
FASEB J. 2017 Oct;31(10):4566-4577. doi: 10.1096/fj.201700078R. Epub 2017 Jul 7.
FASEB J. 2017.
PMID: 28687611
A screening campaign revealed retinol (vitamin A alcohol) and all-trans retinoic acid (vitamin A acid) (RA) as hits that time-dependently (24 h) deplete phosphatidylcholine-bound polyunsaturated fatty acids (PUFA-PCs) from NIH-3T3 mouse fibroblasts while inducing Akt activ …
A screening campaign revealed retinol (vitamin A alcohol) and all-trans retinoic acid (vitamin A acid) (RA) as hits that time-dependently (2 …