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Open science discovery of potent noncovalent SARS-CoV-2 main protease inhibitors.
Boby ML, Fearon D, Ferla M, Filep M, Koekemoer L, Robinson MC; COVID Moonshot Consortium‡; Chodera JD, Lee AA, London N, von Delft A, von Delft F, Achdout H, Aimon A, Alonzi DS, Arbon R, Aschenbrenner JC, Balcomb BH, Bar-David E, Barr H, Ben-Shmuel A, Bennett J, Bilenko VA, Borden B, Boulet P, Bowman GR, Brewitz L, Brun J, Bvnbs S, Calmiano M, Carbery A, Carney DW, Cattermole E, Chang E, Chernyshenko E, Clyde A, Coffland JE, Cohen G, Cole JC, Contini A, Cox L, Croll TI, Cvitkovic M, De Jonghe S, Dias A, Donckers K, Dotson DL, Douangamath A, Duberstein S, Dudgeon T, Dunnett LE, Eastman P, Erez N, Eyermann CJ, Fairhead M, Fate G, Fedorov O, Fernandes RS, Ferrins L, Foster R, Foster H, Fraisse L, Gabizon R, García-Sastre A, Gawriljuk VO, Gehrtz P, Gileadi C, Giroud C, Glass WG, Glen RC, Glinert I, Godoy AS, Gorichko M, Gorrie-Stone T, Griffen EJ, Haneef A, Hassell Hart S, Heer J, Henry M, Hill M, Horrell S, Huang QYJ, Huliak VD, Hurley MFD, Israely T, Jajack A, Jansen J, Jnoff E, Jochmans D, John T, Kaminow B, Kang L, Kantsadi AL, Kenny PW, Kiappes JL, Kinakh SO, Kovar B, Krojer T, La VNT, Laghnimi-Hahn S, Lefker BA, Levy H, Lithgo RM, Logvinenko IG, Lukacik P, Macdonald HB, MacLean … See abstract for full author list ➔ Boby ML, et al. Among authors: morris gm. Science. 2023 Nov 10;382(6671):eabo7201. doi: 10.1126/science.abo7201. Epub 2023 Nov 10. Science. 2023. PMID: 37943932 Free PMC article.
Dr Pugh: a poisoner?
Paull JD, Morris GM. Paull JD, et al. Among authors: morris gm. Anaesth Intensive Care. 2012 Jul;40 Suppl 1:18-21. doi: 10.1177/0310057X120400S104. Anaesth Intensive Care. 2012. PMID: 23230685
Cardiac GR Mediates the Diurnal Rhythm in Ventricular Arrhythmia Susceptibility.
Tikhomirov R, Oakley RH, Anderson C, Xiang Y, Al Othman S, Smith M, Yaar S, Torre E, Li J, Wilson LR, Goulding DR, Donaldson I, Harno E, Soattin L, Shiels HA, Morris GM, Zhang H, Boyett MR, Cidlowski JA, Mesirca P, Mangoni ME, D'Souza A. Tikhomirov R, et al. Among authors: morris gm. Circ Res. 2024 Mar 27. doi: 10.1161/CIRCRESAHA.123.323464. Online ahead of print. Circ Res. 2024. PMID: 38533639
Symptomatic bradyarrhythmias in the athlete-Underlying mechanisms and treatments.
Al-Othman S, Boyett MR, Morris GM, Malhotra A, Mesirca P, Mangoni ME, D'Souza A. Al-Othman S, et al. Among authors: morris gm. Heart Rhythm. 2024 Feb 28:S1547-5271(24)00222-4. doi: 10.1016/j.hrthm.2024.02.050. Online ahead of print. Heart Rhythm. 2024. PMID: 38428449 Free article. Review.
Discovery and pharmacophoric characterization of chemokine network inhibitors using phage-display, saturation mutagenesis and computational modelling.
Vales S, Kryukova J, Chandra S, Smagurauskaite G, Payne M, Clark CJ, Hafner K, Mburu P, Denisov S, Davies G, Outeiral C, Deane CM, Morris GM, Bhattacharya S. Vales S, et al. Among authors: morris gm. Nat Commun. 2023 Sep 16;14(1):5763. doi: 10.1038/s41467-023-41488-z. Nat Commun. 2023. PMID: 37717048 Free PMC article.
255 results