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Page 1
Activation of GPBAR1 attenuates vascular inflammation and atherosclerosis in a mouse model of NAFLD-related cardiovascular disease.
Biagioli M, Marchianò S, Di Giorgio C, Bordoni M, Urbani G, Bellini R, Massa C, Sami Ullah Khan R, Roselli R, Chiara Monti M, Morretta E, Giordano A, Vellecco V, Bucci M, Jilani Iqbal A, Saviano A, Ab Mansour A, Ricci P, Distrutti E, Zampella A, Cieri E, Cirino G, Fiorucci S. Biagioli M, et al. Among authors: morretta e. Biochem Pharmacol. 2023 Dec;218:115900. doi: 10.1016/j.bcp.2023.115900. Epub 2023 Nov 3. Biochem Pharmacol. 2023. PMID: 37926268 Free article.
Opposite effects of the FXR agonist obeticholic acid on Mafg and Nrf2 mediate the development of acute liver injury in rodent models of cholestasis.
Carino A, Biagioli M, Marchianò S, Fiorucci C, Bordoni M, Roselli R, Di Giorgio C, Baldoni M, Ricci P, Monti MC, Morretta E, Zampella A, Distrutti E, Fiorucci S. Carino A, et al. Among authors: morretta e. Biochim Biophys Acta Mol Cell Biol Lipids. 2020 Sep;1865(9):158733. doi: 10.1016/j.bbalip.2020.158733. Epub 2020 May 1. Biochim Biophys Acta Mol Cell Biol Lipids. 2020. PMID: 32371093
Beneficial effects of UDCA and norUDCA in a rodent model of steatosis are linked to modulation of GPBAR1/FXR signaling.
Marchianò S, Biagioli M, Roselli R, Zampella A, Di Giorgio C, Bordoni M, Bellini R, Urbani G, Morretta E, Monti MC, Distrutti E, Fiorucci S. Marchianò S, et al. Among authors: morretta e. Biochim Biophys Acta Mol Cell Biol Lipids. 2022 Nov;1867(11):159218. doi: 10.1016/j.bbalip.2022.159218. Epub 2022 Aug 18. Biochim Biophys Acta Mol Cell Biol Lipids. 2022. PMID: 35985473
Discovery of BAR502, as potent steroidal antagonist of leukemia inhibitory factor receptor for the treatment of pancreatic adenocarcinoma.
Di Giorgio C, Bellini R, Lupia A, Massa C, Bordoni M, Marchianò S, Rosselli R, Sepe V, Rapacciuolo P, Moraca F, Morretta E, Ricci P, Urbani G, Monti MC, Biagioli M, Distrutti E, Catalanotti B, Zampella A, Fiorucci S. Di Giorgio C, et al. Among authors: morretta e. Front Oncol. 2023 Mar 14;13:1140730. doi: 10.3389/fonc.2023.1140730. eCollection 2023. Front Oncol. 2023. PMID: 36998446 Free PMC article.
Repositioning Mifepristone as a Leukaemia Inhibitory Factor Receptor Antagonist for the Treatment of Pancreatic Adenocarcinoma.
Di Giorgio C, Lupia A, Marchianò S, Bordoni M, Bellini R, Massa C, Urbani G, Roselli R, Moraca F, Sepe V, Catalanotti B, Morretta E, Monti MC, Biagioli M, Distrutti E, Zampella A, Fiorucci S. Di Giorgio C, et al. Among authors: morretta e. Cells. 2022 Nov 3;11(21):3482. doi: 10.3390/cells11213482. Cells. 2022. PMID: 36359879 Free PMC article.
Involvement of 3',5'-cyclic inosine monophosphate in cystathionine γ-lyase-dependent regulation of the vascular tone.
Mitidieri E, Vellecco V, Brancaleone V, Vanacore D, Manzo OL, Martin E, Sharina I, Krutsenko Y, Monti MC, Morretta E, Papapetropoulos A, Caliendo G, Frecentese F, Cirino G, Sorrentino R, d'Emmanuele di Villa Bianca R, Bucci M. Mitidieri E, et al. Among authors: morretta e. Br J Pharmacol. 2021 Sep;178(18):3765-3782. doi: 10.1111/bph.15516. Epub 2021 Jun 11. Br J Pharmacol. 2021. PMID: 33931865 Free PMC article.
32 results