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Role of soluble endoglin in BMP9 signaling.
Lawera A, Tong Z, Thorikay M, Redgrave RE, Cai J, van Dinther M, Morrell NW, Afink GB, Charnock-Jones DS, Arthur HM, Ten Dijke P, Li W. Lawera A, et al. Among authors: morrell nw. Proc Natl Acad Sci U S A. 2019 Sep 3;116(36):17800-17808. doi: 10.1073/pnas.1816661116. Epub 2019 Aug 20. Proc Natl Acad Sci U S A. 2019. PMID: 31431534 Free PMC article.
BMP9 mutations cause a vascular-anomaly syndrome with phenotypic overlap with hereditary hemorrhagic telangiectasia.
Wooderchak-Donahue WL, McDonald J, O'Fallon B, Upton PD, Li W, Roman BL, Young S, Plant P, Fülöp GT, Langa C, Morrell NW, Botella LM, Bernabeu C, Stevenson DA, Runo JR, Bayrak-Toydemir P. Wooderchak-Donahue WL, et al. Among authors: morrell nw. Am J Hum Genet. 2013 Sep 5;93(3):530-7. doi: 10.1016/j.ajhg.2013.07.004. Epub 2013 Aug 22. Am J Hum Genet. 2013. PMID: 23972370 Free PMC article.
Targeting BMP signalling in cardiovascular disease and anaemia.
Morrell NW, Bloch DB, ten Dijke P, Goumans MJ, Hata A, Smith J, Yu PB, Bloch KD. Morrell NW, et al. Nat Rev Cardiol. 2016 Feb;13(2):106-20. doi: 10.1038/nrcardio.2015.156. Epub 2015 Oct 13. Nat Rev Cardiol. 2016. PMID: 26461965 Free PMC article. Review.
HIF2α-arginase axis is essential for the development of pulmonary hypertension.
Cowburn AS, Crosby A, Macias D, Branco C, Colaço RD, Southwood M, Toshner M, Crotty Alexander LE, Morrell NW, Chilvers ER, Johnson RS. Cowburn AS, et al. Among authors: morrell nw. Proc Natl Acad Sci U S A. 2016 Aug 2;113(31):8801-6. doi: 10.1073/pnas.1602978113. Epub 2016 Jul 18. Proc Natl Acad Sci U S A. 2016. PMID: 27432976 Free PMC article.
Regulation of the ALK1 ligands, BMP9 and BMP10.
Li W, Salmon RM, Jiang H, Morrell NW. Li W, et al. Among authors: morrell nw. Biochem Soc Trans. 2016 Aug 15;44(4):1135-41. doi: 10.1042/BST20160083. Biochem Soc Trans. 2016. PMID: 27528761 Review.
353 results