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Prolonged fasting times reap greater geroprotective effects when combined with caloric restriction in adult female mice.
Duregon E, Fernandez ME, Martinez Romero J, Di Germanio C, Cabassa M, Voloshchuk R, Ehrlich-Mora MR, Moats JM, Wong S, Bosompra O, Rudderow A, Morrell CH, Camandola S, Price NL, Aon MA, Bernier M, de Cabo R. Duregon E, et al. Among authors: morrell ch. Cell Metab. 2023 Jul 11;35(7):1179-1194.e5. doi: 10.1016/j.cmet.2023.05.003. Cell Metab. 2023. PMID: 37437544
A small erythropoietin derived non-hematopoietic peptide reduces cardiac inflammation, attenuates age associated declines in heart function and prolongs healthspan.
Winicki NM, Nanavati AP, Morrell CH, Moen JM, Axsom JE, Krawczyk M, Petrashevskaya NN, Beyman MG, Ramirez C, Alfaras I, Mitchell SJ, Juhaszova M, Riordon DR, Wang M, Zhang J, Cerami A, Brines M, Sollott SJ, de Cabo R, Lakatta EG. Winicki NM, et al. Among authors: morrell ch. Front Cardiovasc Med. 2023 Jan 18;9:1096887. doi: 10.3389/fcvm.2022.1096887. eCollection 2022. Front Cardiovasc Med. 2023. PMID: 36741836 Free PMC article.
Age-dependent contribution of intrinsic mechanisms to sinoatrial node function in humans.
Weiser-Bitoun I, Mori H, Nabeshima T, Tanaka N, Kudo D, Sasaki W, Narita M, Matsumoto K, Ikeda Y, Arai T, Nakano S, Sumitomo N, Senbonmatsu TA, Matsumoto K, Kato R, Morrell CH, Tsutsui K, Yaniv Y. Weiser-Bitoun I, et al. Among authors: morrell ch. Sci Rep. 2023 Nov 1;13(1):18875. doi: 10.1038/s41598-023-45101-7. Sci Rep. 2023. PMID: 37914708 Free PMC article.
A remarkable adaptive paradigm of heart performance and protection emerges in response to marked cardiac-specific overexpression of ADCY8.
Tarasov KV, Chakir K, Riordon DR, Lyashkov AE, Ahmet I, Perino MG, Silvester AJ, Zhang J, Wang M, Lukyanenko YO, Qu JH, Barrera MC, Juhaszova M, Tarasova YS, Ziman B, Telljohann R, Kumar V, Ranek M, Lammons J, Bychkov R, de Cabo R, Jun S, Keceli G, Gupta A, Yang D, Aon MA, Adamo L, Morrell CH, Otu W, Carroll C, Chambers S, Paolocci N, Huynh T, Pacak K, Weiss R, Field L, Sollott SJ, Lakatta EG. Tarasov KV, et al. Among authors: morrell ch. Elife. 2022 Dec 14;11:e80949. doi: 10.7554/eLife.80949. Elife. 2022. PMID: 36515265 Free PMC article.
66 results