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Blocking Extracellular Chaperones to Improve Cardiac Regeneration.
Seclì L, Sorge M, Morotti A, Brancaccio M. Seclì L, et al. Among authors: morotti a. Front Bioeng Biotechnol. 2020 May 26;8:411. doi: 10.3389/fbioe.2020.00411. eCollection 2020. Front Bioeng Biotechnol. 2020. PMID: 32528937 Free PMC article.
Morgana acts as an oncosuppressor in chronic myeloid leukemia.
Di Savino A, Panuzzo C, Rocca S, Familiari U, Piazza R, Crivellaro S, Carrà G, Ferretti R, Fusella F, Giugliano E, Camporeale A, Franco I, Miniscalco B, Cutrin JC, Turco E, Silengo L, Hirsch E, Rege-Cambrin G, Gambacorti-Passerini C, Pandolfi PP, Papotti M, Saglio G, Tarone G, Morotti A, Brancaccio M. Di Savino A, et al. Among authors: morotti a. Blood. 2015 Apr 2;125(14):2245-53. doi: 10.1182/blood-2014-05-575001. Epub 2015 Feb 12. Blood. 2015. PMID: 25678499 Free article.
Therapeutic inhibition of USP7-PTEN network in chronic lymphocytic leukemia: a strategy to overcome TP53 mutated/deleted clones.
Carrà G, Panuzzo C, Torti D, Parvis G, Crivellaro S, Familiari U, Volante M, Morena D, Lingua MF, Brancaccio M, Guerrasio A, Pandolfi PP, Saglio G, Taulli R, Morotti A. Carrà G, et al. Among authors: morotti a. Oncotarget. 2017 May 30;8(22):35508-35522. doi: 10.18632/oncotarget.16348. Oncotarget. 2017. PMID: 28418900 Free PMC article.
The IKK/NF-κB signaling pathway requires Morgana to drive breast cancer metastasis.
Fusella F, Seclì L, Busso E, Krepelova A, Moiso E, Rocca S, Conti L, Annaratone L, Rubinetto C, Mello-Grand M, Singh V, Chiorino G, Silengo L, Altruda F, Turco E, Morotti A, Oliviero S, Castellano I, Cavallo F, Provero P, Tarone G, Brancaccio M. Fusella F, et al. Among authors: morotti a. Nat Commun. 2017 Nov 21;8(1):1636. doi: 10.1038/s41467-017-01829-1. Nat Commun. 2017. PMID: 29158506 Free PMC article.
IκBα targeting promotes oxidative stress-dependent cell death.
Carrà G, Ermondi G, Riganti C, Righi L, Caron G, Menga A, Capelletto E, Maffeo B, Lingua MF, Fusella F, Volante M, Taulli R, Guerrasio A, Novello S, Brancaccio M, Piazza R, Morotti A. Carrà G, et al. Among authors: morotti a. J Exp Clin Cancer Res. 2021 Apr 16;40(1):136. doi: 10.1186/s13046-021-01921-x. J Exp Clin Cancer Res. 2021. PMID: 33863364 Free PMC article.
Targeting the Extracellular HSP90 Co-Chaperone Morgana Inhibits Cancer Cell Migration and Promotes Anticancer Immunity.
Seclì L, Avalle L, Poggio P, Fragale G, Cannata C, Conti L, Iannucci A, Carrà G, Rubinetto C, Miniscalco B, Hirsch E, Poli V, Morotti A, De Andrea M, Turco E, Cavallo F, Fusella F, Brancaccio M. Seclì L, et al. Among authors: morotti a. Cancer Res. 2021 Sep 15;81(18):4794-4807. doi: 10.1158/0008-5472.CAN-20-3150. Epub 2021 Jun 30. Cancer Res. 2021. PMID: 34193441
262 results