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Fluorosulfonyl- and bis-(beta-chloroethyl)amino-phenylamino functionalized pyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidine derivatives: irreversible antagonists at the human A3 adenosine receptor and molecular modeling studies.
Baraldi PG, Cacciari B, Moro S, Romagnoli R, Ji Xd, Jacobson KA, Gessi S, Borea PA, Spalluto G. Baraldi PG, et al. Among authors: moro s. J Med Chem. 2001 Aug 16;44(17):2735-42. doi: 10.1021/jm010818a. J Med Chem. 2001. PMID: 11495585
Pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidine derivatives as adenosine receptor antagonists. Influence of the N5 substituent on the affinity at the human A 3 and A 2B adenosine receptor subtypes: a molecular modeling investigation.
Pastorin G, Da Ros T, Spalluto G, Deflorian F, Moro S, Cacciari B, Baraldi PG, Gessi S, Varani K, Borea PA. Pastorin G, et al. Among authors: moro s. J Med Chem. 2003 Sep 25;46(20):4287-96. doi: 10.1021/jm030852k. J Med Chem. 2003. PMID: 13678407
1,2,4-triazolo[4,3-a]quinoxalin-1-one moiety as an attractive scaffold to develop new potent and selective human A3 adenosine receptor antagonists: synthesis, pharmacological, and ligand-receptor modeling studies.
Colotta V, Catarzi D, Varano F, Calabri FR, Lenzi O, Filacchioni G, Martini C, Trincavelli L, Deflorian F, Moro S. Colotta V, et al. Among authors: moro s. J Med Chem. 2004 Jul 1;47(14):3580-90. doi: 10.1021/jm031136l. J Med Chem. 2004. PMID: 15214785
1,2,4-Triazolo[1,5-a]quinoxaline as a versatile tool for the design of selective human A3 adenosine receptor antagonists: synthesis, biological evaluation, and molecular modeling studies of 2-(hetero)aryl- and 2-carboxy-substituted derivatives.
Catarzi D, Colotta V, Varano F, Lenzi O, Filacchioni G, Trincavelli L, Martini C, Montopoli C, Moro S. Catarzi D, et al. Among authors: moro s. J Med Chem. 2005 Dec 15;48(25):7932-45. doi: 10.1021/jm0504149. J Med Chem. 2005. PMID: 16335918
Synthesis and biological studies of a new series of 5-heteroarylcarbamoylaminopyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidines as human A3 adenosine receptor antagonists. Influence of the heteroaryl substituent on binding affinity and molecular modeling investigations.
Pastorin G, Da Ros T, Bolcato C, Montopoli C, Moro S, Cacciari B, Baraldi PG, Varani K, Borea PA, Spalluto G. Pastorin G, et al. Among authors: moro s. J Med Chem. 2006 Mar 9;49(5):1720-9. doi: 10.1021/jm051147+. J Med Chem. 2006. PMID: 16509587
410 results