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Intramuscular administration of hexachloroplatinate reverses cyanide-induced metabolic derangements and counteracts severe cyanide poisoning.
Morningstar J, Lee J, Hendry-Hofer T, Witeof A, Lyle LT, Knipp G, MacRae CA, Boss GR, Peterson RT, Davisson VJ, Gerszten RE, Bebarta VS, Mahon S, Brenner M, Nath AK. Morningstar J, et al. FASEB Bioadv. 2019 Feb;1(2):81-92. doi: 10.1096/fba.1024. Epub 2018 Oct 8. FASEB Bioadv. 2019. PMID: 31355359 Free PMC article.
Identification of specific metabolic pathways as druggable targets regulating the sensitivity to cyanide poisoning.
Sips PY, Shi X, Musso G, Nath AK, Zhao Y, Nielson J, Morningstar J, Kelly AE, Mikell B, Buys E, Bebarta V, Rutter J, Davisson VJ, Mahon S, Brenner M, Boss GR, Peterson RT, Gerszten RE, MacRae CA. Sips PY, et al. Among authors: morningstar j. PLoS One. 2018 Jun 7;13(6):e0193889. doi: 10.1371/journal.pone.0193889. eCollection 2018. PLoS One. 2018. PMID: 29879736 Free PMC article.
Cisplatin Analogs Confer Protection against Cyanide Poisoning.
Nath AK, Shi X, Harrison DL, Morningstar JE, Mahon S, Chan A, Sips P, Lee J, MacRae CA, Boss GR, Brenner M, Gerszten RE, Peterson RT. Nath AK, et al. Among authors: morningstar je. Cell Chem Biol. 2017 May 18;24(5):565-575.e4. doi: 10.1016/j.chembiol.2017.03.013. Epub 2017 Apr 13. Cell Chem Biol. 2017. PMID: 28416275 Free PMC article.
Glyoxylate protects against cyanide toxicity through metabolic modulation.
Nielson JR, Nath AK, Doane KP, Shi X, Lee J, Tippetts EG, Saha K, Morningstar J, Hicks KG, Chan A, Zhao Y, Kelly A, Hendry-Hofer TB, Witeof A, Sips PY, Mahon S, Bebarta VS, Davisson VJ, Boss GR, Rutter J, MacRae CA, Brenner M, Gerszten RE, Peterson RT. Nielson JR, et al. Among authors: morningstar j. Sci Rep. 2022 Mar 23;12(1):4982. doi: 10.1038/s41598-022-08803-y. Sci Rep. 2022. PMID: 35322094 Free PMC article.
Plasma Metabolite Profiles in Response to Chronic Exercise.
Brennan AM, Benson M, Morningstar J, Herzig M, Robbins J, Gerszten RE, Ross R. Brennan AM, et al. Among authors: morningstar j. Med Sci Sports Exerc. 2018 Jul;50(7):1480-1486. doi: 10.1249/MSS.0000000000001594. Med Sci Sports Exerc. 2018. PMID: 29509640 Free PMC article. Clinical Trial.
Proteomic profiling reveals biomarkers and pathways in type 2 diabetes risk.
Ngo D, Benson MD, Long JZ, Chen ZZ, Wang R, Nath AK, Keyes MJ, Shen D, Sinha S, Kuhn E, Morningstar JE, Shi X, Peterson BD, Chan C, Katz DH, Tahir UA, Farrell LA, Melander O, Mosley JD, Carr SA, Vasan RS, Larson MG, Smith JG, Wang TJ, Yang Q, Gerszten RE. Ngo D, et al. Among authors: morningstar je. JCI Insight. 2021 Mar 8;6(5):e144392. doi: 10.1172/jci.insight.144392. JCI Insight. 2021. PMID: 33591955 Free PMC article.
Dimethylguanidino valeric acid is a marker of liver fat and predicts diabetes.
O'Sullivan JF, Morningstar JE, Yang Q, Zheng B, Gao Y, Jeanfavre S, Scott J, Fernandez C, Zheng H, O'Connor S, Cohen P, Vasan RS, Long MT, Wilson JG, Melander O, Wang TJ, Fox C, Peterson RT, Clish CB, Corey KE, Gerszten RE. O'Sullivan JF, et al. Among authors: morningstar je. J Clin Invest. 2017 Dec 1;127(12):4394-4402. doi: 10.1172/JCI95995. Epub 2017 Oct 30. J Clin Invest. 2017. PMID: 29083323 Free PMC article. Clinical Trial.
Induced Pluripotent Stem Cell Differentiation Enables Functional Validation of GWAS Variants in Metabolic Disease.
Warren CR, O'Sullivan JF, Friesen M, Becker CE, Zhang X, Liu P, Wakabayashi Y, Morningstar JE, Shi X, Choi J, Xia F, Peters DT, Florido MHC, Tsankov AM, Duberow E, Comisar L, Shay J, Jiang X, Meissner A, Musunuru K, Kathiresan S, Daheron L, Zhu J, Gerszten RE, Deo RC, Vasan RS, O'Donnell CJ, Cowan CA. Warren CR, et al. Among authors: morningstar je. Cell Stem Cell. 2017 Apr 6;20(4):547-557.e7. doi: 10.1016/j.stem.2017.01.010. Cell Stem Cell. 2017. PMID: 28388431 Free article.
57 results