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Resistance to the short term antiproliferative activity of the G-quadruplex ligand 12459 is associated with telomerase overexpression and telomere capping alteration.
Gomez D, Aouali N, Londoño-Vallejo A, Lacroix L, Mégnin-Chanet F, Lemarteleur T, Douarre C, Shin-ya K, Mailliet P, Trentesaux C, Morjani H, Mergny JL, Riou JF. Gomez D, et al. Among authors: morjani h. J Biol Chem. 2003 Dec 12;278(50):50554-62. doi: 10.1074/jbc.M308440200. Epub 2003 Oct 2. J Biol Chem. 2003. PMID: 14525974 Free article.
Mechanism of acridine-based telomerase inhibition and telomere shortening.
Gunaratnam M, Greciano O, Martins C, Reszka AP, Schultes CM, Morjani H, Riou JF, Neidle S. Gunaratnam M, et al. Among authors: morjani h. Biochem Pharmacol. 2007 Sep 1;74(5):679-89. doi: 10.1016/j.bcp.2007.06.011. Epub 2007 Jun 16. Biochem Pharmacol. 2007. PMID: 17631279
Targeting human telomerase for cancer therapeutics.
Guittat L, Alberti P, Gomez D, De Cian A, Pennarun G, Lemarteleur T, Belmokhtar C, Paterski R, Morjani H, Trentesaux C, Mandine E, Boussin F, Mailliet P, Lacroix L, Riou JF, Mergny JL. Guittat L, et al. Among authors: morjani h. Cytotechnology. 2004 Jun;45(1-2):75-90. doi: 10.1007/s10616-004-5127-z. Cytotechnology. 2004. PMID: 19003245 Free PMC article.
130 results