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Report from the in vitro micronucleus assay working group.
Kirsch-Volders M, Sofuni T, Aardema M, Albertini S, Eastmond D, Fenech M, Ishidate M Jr, Kirchner S, Lorge E, Morita T, Norppa H, Surrallés J, Vanhauwaert A, Wakata A. Kirsch-Volders M, et al. Among authors: morita t. Mutat Res. 2003 Oct 7;540(2):153-63. doi: 10.1016/j.mrgentox.2003.07.005. Mutat Res. 2003. PMID: 14550499
Workshop summary: Top concentration for in vitro mammalian cell genotoxicity assays; and report from working group on toxicity measures and top concentration for in vitro cytogenetics assays (chromosome aberrations and micronucleus).
Galloway S, Lorge E, Aardema MJ, Eastmond D, Fellows M, Heflich R, Kirkland D, Levy DD, Lynch AM, Marzin D, Morita T, Schuler M, Speit G. Galloway S, et al. Among authors: morita t. Mutat Res. 2011 Aug 16;723(2):77-83. doi: 10.1016/j.mrgentox.2011.01.003. Epub 2011 Jan 19. Mutat Res. 2011. PMID: 21255675
Evaluation of the sensitivity and specificity of in vivo erythrocyte micronucleus and transgenic rodent gene mutation tests to detect rodent carcinogens.
Morita T, Hamada S, Masumura K, Wakata A, Maniwa J, Takasawa H, Yasunaga K, Hashizume T, Honma M. Morita T, et al. Mutat Res Genet Toxicol Environ Mutagen. 2016 May;802:1-29. doi: 10.1016/j.mrgentox.2016.03.008. Epub 2016 Mar 21. Mutat Res Genet Toxicol Environ Mutagen. 2016. PMID: 27169373 Free article.
IWGT report on quantitative approaches to genotoxicity risk assessment II. Use of point-of-departure (PoD) metrics in defining acceptable exposure limits and assessing human risk.
MacGregor JT, Frötschl R, White PA, Crump KS, Eastmond DA, Fukushima S, Guérard M, Hayashi M, Soeteman-Hernández LG, Johnson GE, Kasamatsu T, Levy DD, Morita T, Müller L, Schoeny R, Schuler MJ, Thybaud V. MacGregor JT, et al. Among authors: morita t. Mutat Res Genet Toxicol Environ Mutagen. 2015 May 1;783:66-78. doi: 10.1016/j.mrgentox.2014.10.008. Epub 2014 Oct 27. Mutat Res Genet Toxicol Environ Mutagen. 2015. PMID: 25953401 Free article.
IWGT report on quantitative approaches to genotoxicity risk assessment I. Methods and metrics for defining exposure-response relationships and points of departure (PoDs).
MacGregor JT, Frötschl R, White PA, Crump KS, Eastmond DA, Fukushima S, Guérard M, Hayashi M, Soeteman-Hernández LG, Kasamatsu T, Levy DD, Morita T, Müller L, Schoeny R, Schuler MJ, Thybaud V, Johnson GE. MacGregor JT, et al. Among authors: morita t. Mutat Res Genet Toxicol Environ Mutagen. 2015 May 1;783:55-65. doi: 10.1016/j.mrgentox.2014.09.011. Epub 2014 Oct 13. Mutat Res Genet Toxicol Environ Mutagen. 2015. PMID: 25953400 Free article.
In vivo erythrocyte micronucleus assay III. Validation and regulatory acceptance of automated scoring and the use of rat peripheral blood reticulocytes, with discussion of non-hematopoietic target cells and a single dose-level limit test.
Hayashi M, MacGregor JT, Gatehouse DG, Blakey DH, Dertinger SD, Abramsson-Zetterberg L, Krishna G, Morita T, Russo A, Asano N, Suzuki H, Ohyama W, Gibson D; In Vivo Micronucleus Assay Working Group, IWGT. Hayashi M, et al. Among authors: morita t. Mutat Res. 2007 Feb 3;627(1):10-30. doi: 10.1016/j.mrgentox.2006.08.010. Epub 2006 Dec 6. Mutat Res. 2007. PMID: 17157053
3,978 results