Morishima-Kawashima M - Search Results

1

Alzheimer's disease: beta-Amyloid protein and tau.

Morishima-Kawashima M, Ihara Y. Morishima-Kawashima M, et al. J Neurosci Res. 2002 Nov 1;70(3):392-401. doi: 10.1002/jnr.10355. J Neurosci Res. 2002. PMID: 12391602 Review.

2

Distinct mechanisms by mutant presenilin 1 and 2 leading to increased intracellular levels of amyloid beta-protein 42 in Chinese hamster ovary cells.

Qi Y, Morishima-Kawashima M, Sato T, Mitsumori R, Ihara Y. Qi Y, et al. Biochemistry. 2003 Feb 4;42(4):1042-52. doi: 10.1021/bi0267590. Biochemistry. 2003. PMID: 12549925

3

Potential link between amyloid beta-protein 42 and C-terminal fragment gamma 49-99 of beta-amyloid precursor protein.

Sato T, Dohmae N, Qi Y, Kakuda N, Misonou H, Mitsumori R, Maruyama H, Koo EH, Haass C, Takio K, Morishima-Kawashima M, Ishiura S, Ihara Y. Sato T, et al. J Biol Chem. 2003 Jul 4;278(27):24294-301. doi: 10.1074/jbc.M211161200. Epub 2003 Apr 21. J Biol Chem. 2003. PMID: 12707272 Free article.

4

Truncated carboxyl-terminal fragments of beta-amyloid precursor protein are processed to amyloid beta-proteins 40 and 42.

Funamoto S, Morishima-Kawashima M, Tanimura Y, Hirotani N, Saido TC, Ihara Y. Funamoto S, et al. Biochemistry. 2004 Oct 26;43(42):13532-40. doi: 10.1021/bi049399k. Biochemistry. 2004. PMID: 15491160

5

Longer forms of amyloid beta protein: implications for the mechanism of intramembrane cleavage by gamma-secretase.

Qi-Takahara Y, Morishima-Kawashima M, Tanimura Y, Dolios G, Hirotani N, Horikoshi Y, Kametani F, Maeda M, Saido TC, Wang R, Ihara Y. Qi-Takahara Y, et al. J Neurosci. 2005 Jan 12;25(2):436-45. doi: 10.1523/JNEUROSCI.1575-04.2005. J Neurosci. 2005. PMID: 15647487 Free PMC article.

6

Blocking the cleavage at midportion between gamma- and epsilon-sites remarkably suppresses the generation of amyloid beta-protein.

Sato T, Tanimura Y, Hirotani N, Saido TC, Morishima-Kawashima M, Ihara Y. Sato T, et al. FEBS Lett. 2005 May 23;579(13):2907-12. doi: 10.1016/j.febslet.2005.04.037. FEBS Lett. 2005. PMID: 15890346 Free article.

7

DAPT-induced intracellular accumulations of longer amyloid beta-proteins: further implications for the mechanism of intramembrane cleavage by gamma-secretase.

Yagishita S, Morishima-Kawashima M, Tanimura Y, Ishiura S, Ihara Y. Yagishita S, et al. Biochemistry. 2006 Mar 28;45(12):3952-60. doi: 10.1021/bi0521846. Biochemistry. 2006. PMID: 16548522

8

Effects of human apolipoprotein E isoforms on the amyloid beta-protein concentration and lipid composition in brain low-density membrane domains.

Morishima-Kawashima M, Han X, Tanimura Y, Hamanaka H, Kobayashi M, Sakurai T, Yokoyama M, Wada K, Nukina N, Fujita SC, Ihara Y. Morishima-Kawashima M, et al. J Neurochem. 2007 May;101(4):949-58. doi: 10.1111/j.1471-4159.2006.04400.x. J Neurochem. 2007. PMID: 17472586 Free PMC article.

9

Enzymatic characteristics of I213T mutant presenilin-1/gamma-secretase in cell models and knock-in mouse brains: familial Alzheimer disease-linked mutation impairs gamma-site cleavage of amyloid precursor protein C-terminal fragment beta.

Shimojo M, Sahara N, Mizoroki T, Funamoto S, Morishima-Kawashima M, Kudo T, Takeda M, Ihara Y, Ichinose H, Takashima A. Shimojo M, et al. Among authors: morishima kawashima m. J Biol Chem. 2008 Jun 13;283(24):16488-96. doi: 10.1074/jbc.M801279200. Epub 2008 Apr 21. J Biol Chem. 2008. PMID: 18430735 Free article.

10

gamma-Secretase: successive tripeptide and tetrapeptide release from the transmembrane domain of beta-carboxyl terminal fragment.

Takami M, Nagashima Y, Sano Y, Ishihara S, Morishima-Kawashima M, Funamoto S, Ihara Y. Takami M, et al. Among authors: morishima kawashima m. J Neurosci. 2009 Oct 14;29(41):13042-52. doi: 10.1523/JNEUROSCI.2362-09.2009. J Neurosci. 2009. PMID: 19828817 Free PMC article.

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