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Unique molecular and functional features of extramedullary hematopoietic stem and progenitor cell reservoirs in humans.
Mende N, Bastos HP, Santoro A, Mahbubani KT, Ciaurro V, Calderbank EF, Quiroga Londoño M, Sham K, Mantica G, Morishima T, Mitchell E, Lidonnici MR, Meier-Abt F, Hayler D, Jardine L, Curd A, Haniffa M, Ferrari G, Takizawa H, Wilson NK, Göttgens B, Saeb-Parsy K, Frontini M, Laurenti E. Mende N, et al. Among authors: morishima t. Blood. 2022 Jun 9;139(23):3387-3401. doi: 10.1182/blood.2021013450. Blood. 2022. PMID: 35073399 Free PMC article.
GPRC5C drives branched-chain amino acid metabolism in leukemogenesis.
Zhang YW, Velasco-Hernandez T, Mess J, Lalioti ME, Romero-Mulero MC, Obier N, Karantzelis N, Rettkowski J, Schönberger K, Karabacz N, Jäcklein K, Morishima T, Trincado JL, Romecin P, Martinez A, Takizawa H, Shoumariyeh K, Renders S, Zeiser R, Pahl HL, Béliveau F, Hébert J, Lehnertz B, Sauvageau G, Menendez P, Cabezas-Wallscheid N. Zhang YW, et al. Among authors: morishima t. Blood Adv. 2023 Dec 26;7(24):7525-7538. doi: 10.1182/bloodadvances.2023010460. Blood Adv. 2023. PMID: 37639313 Free PMC article.
LMO2 activation by deacetylation is indispensable for hematopoiesis and T-ALL leukemogenesis.
Morishima T, Krahl AC, Nasri M, Xu Y, Aghaallaei N, Findik B, Klimiankou M, Ritter M, Hartmann MD, Gloeckner CJ, Stefanczyk S, Lindner C, Oswald B, Bernhard R, Hähnel K, Hermanutz-Klein U, Ebinger M, Handgretinger R, Casadei N, Welte K, Andre M, Müller P, Bajoghli B, Skokowa J. Morishima T, et al. Blood. 2019 Oct 3;134(14):1159-1175. doi: 10.1182/blood.2019000095. Epub 2019 Jul 31. Blood. 2019. PMID: 31366618 Free PMC article.
Humanized mouse models with endogenously developed human natural killer cells for in vivo immunogenicity testing of HLA class I-edited iPSC-derived cells.
Flahou C, Morishima T, Higashi N, Hayashi Y, Xu H, Wang B, Zhang C, Ninomiya A, Qiu WY, Yuzuriha A, Suzuki D, Nakamura S, Manz M, Kaneko S, Hotta A, Takizawa H, Eto K, Sugimoto N. Flahou C, et al. Among authors: morishima t. Biochem Biophys Res Commun. 2023 Jun 25;662:76-83. doi: 10.1016/j.bbrc.2023.04.067. Epub 2023 Apr 20. Biochem Biophys Res Commun. 2023. PMID: 37099813
590 results