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Osteoblast-derived vesicles induce a switch from bone-formation to bone-resorption in vivo.
Uenaka M, Yamashita E, Kikuta J, Morimoto A, Ao T, Mizuno H, Furuya M, Hasegawa T, Tsukazaki H, Sudo T, Nishikawa K, Okuzaki D, Motooka D, Kosaka N, Sugihara F, Boettger T, Braun T, Ochiya T, Ishii M. Uenaka M, et al. Among authors: morimoto a. Nat Commun. 2022 Feb 24;13(1):1066. doi: 10.1038/s41467-022-28673-2. Nat Commun. 2022. PMID: 35210428 Free PMC article.
Direct cell-cell contact between mature osteoblasts and osteoclasts dynamically controls their functions in vivo.
Furuya M, Kikuta J, Fujimori S, Seno S, Maeda H, Shirazaki M, Uenaka M, Mizuno H, Iwamoto Y, Morimoto A, Hashimoto K, Ito T, Isogai Y, Kashii M, Kaito T, Ohba S, Chung UI, Lichtler AC, Kikuchi K, Matsuda H, Yoshikawa H, Ishii M. Furuya M, et al. Among authors: morimoto a. Nat Commun. 2018 Jan 19;9(1):300. doi: 10.1038/s41467-017-02541-w. Nat Commun. 2018. PMID: 29352112 Free PMC article.
SLPI is a critical mediator that controls PTH-induced bone formation.
Morimoto A, Kikuta J, Nishikawa K, Sudo T, Uenaka M, Furuya M, Hasegawa T, Hashimoto K, Tsukazaki H, Seno S, Nakamura A, Okuzaki D, Sugihara F, Ninomiya A, Yoshimura T, Takao-Kawabata R, Matsuda H, Ishii M. Morimoto A, et al. Nat Commun. 2021 Apr 9;12(1):2136. doi: 10.1038/s41467-021-22402-x. Nat Commun. 2021. PMID: 33837198 Free PMC article.
Single-cell transcriptomics of human cholesteatoma identifies an activin A-producing osteoclastogenic fibroblast subset inducing bone destruction.
Shimizu K, Kikuta J, Ohta Y, Uchida Y, Miyamoto Y, Morimoto A, Yari S, Sato T, Kamakura T, Oshima K, Imai R, Liu YC, Okuzaki D, Hara T, Motooka D, Emoto N, Inohara H, Ishii M. Shimizu K, et al. Among authors: morimoto a. Nat Commun. 2023 Aug 3;14(1):4417. doi: 10.1038/s41467-023-40094-3. Nat Commun. 2023. PMID: 37537159 Free PMC article.
Clinical and laboratory findings characterizing the need for systemic corticosteroids and nonsteroidal systemic therapies, and the predicted outcomes in cutaneous polyarteritis nodosa: A single-centre retrospective analysis.
Tanaka R, Tanese K, Ito Y, Takeuchi S, Morimoto A, Sujino K, Amagai M, Tanikawa A. Tanaka R, et al. Among authors: morimoto a. Clin Exp Dermatol. 2024 May 9:llae143. doi: 10.1093/ced/llae143. Online ahead of print. Clin Exp Dermatol. 2024. PMID: 38722089
696 results