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Insulin resistance increases the risk of incident type 2 diabetes mellitus in patients with non-alcoholic fatty liver disease.
Seko Y, Sumida Y, Tanaka S, Mori K, Taketani H, Ishiba H, Hara T, Okajima A, Umemura A, Nishikawa T, Yamaguchi K, Moriguchi M, Kanemasa K, Yasui K, Imai S, Shimada K, Itoh Y. Seko Y, et al. Among authors: moriguchi m. Hepatol Res. 2018 Feb;48(3):E42-E51. doi: 10.1111/hepr.12925. Epub 2017 Jul 20. Hepatol Res. 2018. PMID: 28628263
A green tea polyphenol, epigalocatechin-3-gallate, induces apoptosis of human hepatocellular carcinoma, possibly through inhibition of Bcl-2 family proteins.
Nishikawa T, Nakajima T, Moriguchi M, Jo M, Sekoguchi S, Ishii M, Takashima H, Katagishi T, Kimura H, Minami M, Itoh Y, Kagawa K, Okanoue T. Nishikawa T, et al. Among authors: moriguchi m. J Hepatol. 2006 Jun;44(6):1074-82. doi: 10.1016/j.jhep.2005.11.045. Epub 2005 Dec 28. J Hepatol. 2006. PMID: 16481065
Blockade of interleukin 6 signalling ameliorates systemic insulin resistance through upregulation of glucose uptake in skeletal muscle and improves hepatic steatosis in high-fat diet fed mice.
Yamaguchi K, Nishimura T, Ishiba H, Seko Y, Okajima A, Fujii H, Tochiki N, Umemura A, Moriguchi M, Sumida Y, Mitsuyoshi H, Yasui K, Minami M, Okanoue T, Itoh Y. Yamaguchi K, et al. Among authors: moriguchi m. Liver Int. 2015 Feb;35(2):550-61. doi: 10.1111/liv.12645. Epub 2014 Aug 12. Liver Int. 2015. PMID: 25066281
Lower levels of insulin-like growth factor-1 standard deviation score are associated with histological severity of non-alcoholic fatty liver disease.
Sumida Y, Yonei Y, Tanaka S, Mori K, Kanemasa K, Imai S, Taketani H, Hara T, Seko Y, Ishiba H, Okajima A, Yamaguchi K, Moriguchi M, Mitsuyoshi H, Yasui K, Minami M, Itoh Y. Sumida Y, et al. Among authors: moriguchi m. Hepatol Res. 2015 Jul;45(7):771-81. doi: 10.1111/hepr.12408. Epub 2014 Sep 30. Hepatol Res. 2015. PMID: 25163357
358 results