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Trophoblast cell surface antigen-2 phosphorylation triggered by binding of galectin-3 drives metastasis through down-regulation of E-cadherin.
Iwamoto S, Mori Y, Yamashita T, Ojima K, Akita K, Togano S, Kushiyama S, Yashiro M, Yatera Y, Yamaguchi T, Komiyama A, Sago Y, Itano N, Nakada H. Iwamoto S, et al. Among authors: mori y. J Biol Chem. 2023 Aug;299(8):104971. doi: 10.1016/j.jbc.2023.104971. Epub 2023 Jun 27. J Biol Chem. 2023. PMID: 37380081 Free PMC article.
MUC1 protein induces urokinase-type plasminogen activator (uPA) by forming a complex with NF-κB p65 transcription factor and binding to the uPA promoter, leading to enhanced invasiveness of cancer cells.
Mori Y, Akita K, Tanida S, Ishida A, Toda M, Inoue M, Yashiro M, Sawada T, Hirakawa K, Nakada H. Mori Y, et al. J Biol Chem. 2014 Dec 19;289(51):35193-204. doi: 10.1074/jbc.M114.586461. Epub 2014 Nov 4. J Biol Chem. 2014. PMID: 25371209 Free PMC article.
Induction of Trop-2 expression through the binding of galectin-3 to MUC1.
Yamashita T, Mori Y, Alzaaqi SM, Yashiro M, Sawada T, Hirakawa K, Nakada H. Yamashita T, et al. Among authors: mori y. Biochem Biophys Res Commun. 2019 Aug 13;516(1):44-49. doi: 10.1016/j.bbrc.2019.06.003. Epub 2019 Jun 10. Biochem Biophys Res Commun. 2019. PMID: 31196625
5,667 results