Mori M - Search Results

1

Discovery of MDM2-p53 and MDM4-p53 protein-protein interactions small molecule dual inhibitors.

Espadinha M, Lopes EA, Marques V, Amaral JD, Dos Santos DJVA, Mori M, Daniele S, Piccarducci R, Zappelli E, Martini C, Rodrigues CMP, Santos MMM. Espadinha M, et al. Among authors: mori m. Eur J Med Chem. 2022 Nov 5;241:114637. doi: 10.1016/j.ejmech.2022.114637. Epub 2022 Aug 5. Eur J Med Chem. 2022. PMID: 35961068 Free article.

2

2-Hydroxypropyl-β-cyclodextrin strongly improves water solubility and anti-proliferative activity of pyrazolo[3,4-d]pyrimidines Src-Abl dual inhibitors.

Dreassi E, Zizzari AT, Mori M, Filippi I, Belfiore A, Naldini A, Carraro F, Santucci A, Schenone S, Botta M. Dreassi E, et al. Among authors: mori m. Eur J Med Chem. 2010 Dec;45(12):5958-64. doi: 10.1016/j.ejmech.2010.09.062. Epub 2010 Oct 8. Eur J Med Chem. 2010. PMID: 20970221

3

Computational techniques are valuable tools for the discovery of protein-protein interaction inhibitors: the 14-3-3σ case.

Corradi V, Mancini M, Santucci MA, Carlomagno T, Sanfelice D, Mori M, Vignaroli G, Falchi F, Manetti F, Radi M, Botta M. Corradi V, et al. Among authors: mori m. Bioorg Med Chem Lett. 2011 Nov 15;21(22):6867-71. doi: 10.1016/j.bmcl.2011.09.011. Epub 2011 Sep 10. Bioorg Med Chem Lett. 2011. PMID: 21962576

4

Design, Palladium-Catalyzed Synthesis, and Biological Investigation of 2-Substituted 3-Aroylquinolin-4(1H)-ones as Inhibitors of the Hedgehog Signaling Pathway.

Alfonsi R, Botta B, Cacchi S, Di Marcotullio L, Fabrizi G, Faedda R, Goggiamani A, Iazzetti A, Mori M. Alfonsi R, et al. Among authors: mori m. J Med Chem. 2017 Feb 23;60(4):1469-1477. doi: 10.1021/acs.jmedchem.6b01135. Epub 2017 Feb 10. J Med Chem. 2017. PMID: 28122186

5

Novel coumarin- and quinolinone-based polycycles as cell division cycle 25-A and -C phosphatases inhibitors induce proliferation arrest and apoptosis in cancer cells.

Zwergel C, Czepukojc B, Evain-Bana E, Xu Z, Stazi G, Mori M, Patsilinakos A, Mai A, Botta B, Ragno R, Bagrel D, Kirsch G, Meiser P, Jacob C, Montenarh M, Valente S. Zwergel C, et al. Among authors: mori m. Eur J Med Chem. 2017 Jul 7;134:316-333. doi: 10.1016/j.ejmech.2017.04.012. Epub 2017 Apr 10. Eur J Med Chem. 2017. PMID: 28431339

6

Structure, Function, Involvement in Diseases and Targeting of 14-3-3 Proteins: An Update.

Cau Y, Valensin D, Mori M, Draghi S, Botta M. Cau Y, et al. Among authors: mori m. Curr Med Chem. 2018;25(1):5-21. doi: 10.2174/0929867324666170426095015. Curr Med Chem. 2018. PMID: 28462702 Review.

7

Naturally occurring Diels-Alder-type adducts from Morus nigra as potent inhibitors of Mycobacterium tuberculosis protein tyrosine phosphatase B.

Mascarello A, Orbem Menegatti AC, Calcaterra A, Martins PGA, Chiaradia-Delatorre LD, D'Acquarica I, Ferrari F, Pau V, Sanna A, De Logu A, Botta M, Botta B, Terenzi H, Mori M. Mascarello A, et al. Among authors: mori m. Eur J Med Chem. 2018 Jan 20;144:277-288. doi: 10.1016/j.ejmech.2017.11.087. Epub 2017 Dec 7. Eur J Med Chem. 2018. PMID: 29275228

8

Synergistic inhibition of the Hedgehog pathway by newly designed Smo and Gli antagonists bearing the isoflavone scaffold.

Berardozzi S, Bernardi F, Infante P, Ingallina C, Toscano S, De Paolis E, Alfonsi R, Caimano M, Botta B, Mori M, Di Marcotullio L, Ghirga F. Berardozzi S, et al. Among authors: mori m. Eur J Med Chem. 2018 Aug 5;156:554-562. doi: 10.1016/j.ejmech.2018.07.017. Epub 2018 Jul 9. Eur J Med Chem. 2018. PMID: 30025349

9

Chemically stable inhibitors of 14-3-3 protein-protein interactions derived from BV02.

Iralde-Lorente L, Cau Y, Clementi L, Franci L, Tassone G, Valensin D, Mori M, Angelucci A, Chiariello M, Botta M. Iralde-Lorente L, et al. Among authors: mori m. J Enzyme Inhib Med Chem. 2019 Dec;34(1):657-664. doi: 10.1080/14756366.2019.1574779. J Enzyme Inhib Med Chem. 2019. PMID: 30727786 Free PMC article.

10

Identification of a new family of pyrazolo[3,4-d]pyrimidine derivatives as multitarget Fyn-Blk-Lyn inhibitors active on B- and T-lymphoma cell lines.

Fallacara AL, Passannanti R, Mori M, Iovenitti G, Musumeci F, Greco C, Crespan E, Kissova M, Maga G, Tarantelli C, Spriano F, Gaudio E, Bertoni F, Botta M, Schenone S. Fallacara AL, et al. Among authors: mori m. Eur J Med Chem. 2019 Nov 1;181:111545. doi: 10.1016/j.ejmech.2019.07.048. Epub 2019 Jul 18. Eur J Med Chem. 2019. PMID: 31400706

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