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ATRX loss in glioma results in dysregulation of cell-cycle phase transition and ATM inhibitor radio-sensitization.
Qin T, Mullan B, Ravindran R, Messinger D, Siada R, Cummings JR, Harris M, Muruganand A, Pyaram K, Miklja Z, Reiber M, Garcia T, Tran D, Danussi C, Brosnan-Cashman J, Pratt D, Zhao X, Rehemtulla A, Sartor MA, Venneti S, Meeker AK, Huse JT, Morgan MA, Lowenstein PR, Castro MG, Yadav VN, Koschmann C. Qin T, et al. Among authors: morgan ma. Cell Rep. 2022 Jan 11;38(2):110216. doi: 10.1016/j.celrep.2021.110216. Cell Rep. 2022. PMID: 35021084 Free PMC article.
A Pan-ALDH1A Inhibitor Induces Necroptosis in Ovarian Cancer Stem-like Cells.
Chefetz I, Grimley E, Yang K, Hong L, Vinogradova EV, Suciu R, Kovalenko I, Karnak D, Morgan CA, Chtcherbinine M, Buchman C, Huddle B, Barraza S, Morgan M, Bernstein KA, Yoon E, Lombard DB, Bild A, Mehta G, Romero I, Chiang CY, Landen C, Cravatt B, Hurley TD, Larsen SD, Buckanovich RJ. Chefetz I, et al. Cell Rep. 2019 Mar 12;26(11):3061-3075.e6. doi: 10.1016/j.celrep.2019.02.032. Cell Rep. 2019. PMID: 30865894 Free PMC article.
UAE1 inhibition mediates the unfolded protein response, DNA damage and caspase-dependent cell death in pancreatic cancer.
Liu Y, Awadia S, Delaney A, Sitto M, Engelke CG, Patel H, Calcaterra A, Zelenka-Wang S, Lee H, Contessa J, Neamati N, Ljungman M, Lawrence TS, Morgan MA, Rehemtulla A. Liu Y, et al. Among authors: morgan ma. Transl Oncol. 2020 Nov;13(11):100834. doi: 10.1016/j.tranon.2020.100834. Epub 2020 Jul 17. Transl Oncol. 2020. PMID: 32688248 Free PMC article.
Purine metabolism regulates DNA repair and therapy resistance in glioblastoma.
Zhou W, Yao Y, Scott AJ, Wilder-Romans K, Dresser JJ, Werner CK, Sun H, Pratt D, Sajjakulnukit P, Zhao SG, Davis M, Nelson BS, Halbrook CJ, Zhang L, Gatto F, Umemura Y, Walker AK, Kachman M, Sarkaria JN, Xiong J, Morgan MA, Rehemtualla A, Castro MG, Lowenstein P, Chandrasekaran S, Lawrence TS, Lyssiotis CA, Wahl DR. Zhou W, et al. Among authors: morgan ma. Nat Commun. 2020 Jul 30;11(1):3811. doi: 10.1038/s41467-020-17512-x. Nat Commun. 2020. PMID: 32732914 Free PMC article.
Expression of the Androgen Receptor Governs Radiation Resistance in a Subset of Glioblastomas Vulnerable to Antiandrogen Therapy.
Werner CK, Nna UJ, Sun H, Wilder-Romans K, Dresser J, Kothari AU, Zhou W, Yao Y, Rao A, Stallard S, Koschmann C, Bor T, Debinski W, Hegedus AM, Morgan MA, Venneti S, Baskin-Bey E, Spratt DE, Colman H, Sarkaria JN, Chinnaiyan AM, Eisner JR, Speers C, Lawrence TS, Strowd RE, Wahl DR. Werner CK, et al. Among authors: morgan ma. Mol Cancer Ther. 2020 Oct;19(10):2163-2174. doi: 10.1158/1535-7163.MCT-20-0095. Epub 2020 Aug 12. Mol Cancer Ther. 2020. PMID: 32796101 Free PMC article.
552 results