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A subset of type-II collagen-binding antibodies prevents experimental arthritis by inhibiting FCGR3 signaling in neutrophils.
Nat Commun. 2023 Sep 23;14(1):5949. doi: 10.1038/s41467-023-41561-7.
Nat Commun. 2023.
PMID: 37741824
Free PMC article.
A subset of antibodies targeting citrullinated proteins confers protection from rheumatoid arthritis.
He Y, Ge C, Moreno-Giró À, Xu B, Beusch CM, Sandor K, Su J, Cheng L, Lönnblom E, Lundqvist C, Slot LM, Tong D, Urbonaviciute V, Liang B, Li T, Lahore GF, Aoun M, Malmström V, Rispens T, Ernfors P, Svensson CI, Scherer HU, Toes REM, Gjertsson I, Ekwall O, Zubarev RA, Holmdahl R.
He Y, et al. Among authors: moreno giro a.
Nat Commun. 2023 Feb 8;14(1):691. doi: 10.1038/s41467-023-36257-x.
Nat Commun. 2023.
PMID: 36754962
Free PMC article.
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Fcgr2b and Fcgr3 are the major genetic factors for cartilage antibody-induced arthritis, overriding the effect of Hc encoding complement C5.
Xu Z, Moreno-Giró À, Zhao D, Krämer A, Pandey RK, Xu B, Lundström SL, Holmdahl R.
Xu Z, et al. Among authors: moreno giro a.
Eur J Immunol. 2024 Apr;54(4):e2350659. doi: 10.1002/eji.202350659. Epub 2024 Feb 5.
Eur J Immunol. 2024.
PMID: 38314895
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