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Multi-Omic analyses characterize the ceramide/sphingomyelin pathway as a therapeutic target in Alzheimer's disease.
Baloni P, Arnold M, Buitrago L, Nho K, Moreno H, Huynh K, Brauner B, Louie G, Kueider-Paisley A, Suhre K, Saykin AJ, Ekroos K, Meikle PJ, Hood L, Price ND; Alzheimer’s Disease Metabolomics Consortium; Doraiswamy PM, Funk CC, Hernández AI, Kastenmüller G, Baillie R, Han X, Kaddurah-Daouk R. Baloni P, et al. Among authors: moreno h. Commun Biol. 2022 Oct 8;5(1):1074. doi: 10.1038/s42003-022-04011-6. Commun Biol. 2022. PMID: 36209301 Free PMC article.
Role of Liver X Receptor in AD Pathophysiology.
Sandoval-Hernández AG, Buitrago L, Moreno H, Cardona-Gómez GP, Arboleda G. Sandoval-Hernández AG, et al. Among authors: moreno h. PLoS One. 2015 Dec 31;10(12):e0145467. doi: 10.1371/journal.pone.0145467. eCollection 2015. PLoS One. 2015. PMID: 26720273 Free PMC article.
Perspective on calcium and Alzheimer's disease.
Llinas R, Moreno H. Llinas R, et al. Among authors: moreno h. Alzheimers Dement. 2017 Feb;13(2):196-197. doi: 10.1016/j.jalz.2017.01.004. Epub 2017 Jan 26. Alzheimers Dement. 2017. PMID: 28130964 No abstract available.
Neuronal hyperactivity due to loss of inhibitory tone in APOE4 mice lacking Alzheimer's disease-like pathology.
Nuriel T, Angulo SL, Khan U, Ashok A, Chen Q, Figueroa HY, Emrani S, Liu L, Herman M, Barrett G, Savage V, Buitrago L, Cepeda-Prado E, Fung C, Goldberg E, Gross SS, Hussaini SA, Moreno H, Small SA, Duff KE. Nuriel T, et al. Among authors: moreno h. Nat Commun. 2017 Nov 13;8(1):1464. doi: 10.1038/s41467-017-01444-0. Nat Commun. 2017. PMID: 29133888 Free PMC article.
Cerebrovascular disease promotes tau pathology in Alzheimer's disease.
Laing KK, Simoes S, Baena-Caldas GP, Lao PJ, Kothiya M, Igwe KC, Chesebro AG, Houck AL, Pedraza L, Hernández AI, Li J, Zimmerman ME, Luchsinger JA, Barone FC, Moreno H, Brickman AM; Alzheimer’s Disease Neuroimaging Initiative. Laing KK, et al. Among authors: moreno h. Brain Commun. 2020 Aug 19;2(2):fcaa132. doi: 10.1093/braincomms/fcaa132. eCollection 2020. Brain Commun. 2020. PMID: 33215083 Free PMC article.
Metabolic Network Analysis Reveals Altered Bile Acid Synthesis and Metabolism in Alzheimer's Disease.
Baloni P, Funk CC, Yan J, Yurkovich JT, Kueider-Paisley A, Nho K, Heinken A, Jia W, Mahmoudiandehkordi S, Louie G, Saykin AJ, Arnold M, Kastenmüller G, Griffiths WJ, Thiele I; Alzheimer’s Disease Metabolomics Consortium; Kaddurah-Daouk R, Price ND. Baloni P, et al. Cell Rep Med. 2020 Nov 17;1(8):100138. doi: 10.1016/j.xcrm.2020.100138. eCollection 2020 Nov 17. Cell Rep Med. 2020. PMID: 33294859 Free PMC article.
Alzheimer's vulnerable brain region relies on a distinct retromer core dedicated to endosomal recycling.
Simoes S, Guo J, Buitrago L, Qureshi YH, Feng X, Kothiya M, Cortes E, Patel V, Kannan S, Kim YH, Chang KT; Alzheimer's Disease Neuroimaging Initiative; Hussaini SA, Moreno H, Di Paolo G, Andersen OM, Small SA. Simoes S, et al. Among authors: moreno h. Cell Rep. 2021 Dec 28;37(13):110182. doi: 10.1016/j.celrep.2021.110182. Cell Rep. 2021. PMID: 34965419 Free PMC article.
390 results