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Page 1
Cognitive impairment and autistic-like behaviour in SAPAP4-deficient mice.
Schob C, Morellini F, Ohana O, Bakota L, Hrynchak MV, Brandt R, Brockmann MD, Cichon N, Hartung H, Hanganu-Opatz IL, Kraus V, Scharf S, Herrmans-Borgmeyer I, Schweizer M, Kuhl D, Wöhr M, Vörckel KJ, Calzada-Wack J, Fuchs H, Gailus-Durner V, Hrabě de Angelis M, Garner CC, Kreienkamp HJ, Kindler S. Schob C, et al. Among authors: morellini f. Transl Psychiatry. 2019 Jan 16;9(1):7. doi: 10.1038/s41398-018-0327-z. Transl Psychiatry. 2019. PMID: 30664629 Free PMC article.
The insulin receptor substrate of 53 kDa (IRSp53) limits hippocampal synaptic plasticity.
Sawallisch C, Berhörster K, Disanza A, Mantoani S, Kintscher M, Stoenica L, Dityatev A, Sieber S, Kindler S, Morellini F, Schweizer M, Boeckers TM, Korte M, Scita G, Kreienkamp HJ. Sawallisch C, et al. Among authors: morellini f. J Biol Chem. 2009 Apr 3;284(14):9225-36. doi: 10.1074/jbc.M808425200. Epub 2009 Feb 10. J Biol Chem. 2009. PMID: 19208628 Free PMC article.
Treatment during a vulnerable developmental period rescues a genetic epilepsy.
Marguet SL, Le-Schulte VT, Merseburg A, Neu A, Eichler R, Jakovcevski I, Ivanov A, Hanganu-Opatz IL, Bernard C, Morellini F, Isbrandt D. Marguet SL, et al. Among authors: morellini f. Nat Med. 2015 Dec;21(12):1436-44. doi: 10.1038/nm.3987. Epub 2015 Nov 23. Nat Med. 2015. PMID: 26594844
The serine protease inhibitor neuroserpin is required for normal synaptic plasticity and regulates learning and social behavior.
Reumann R, Vierk R, Zhou L, Gries F, Kraus V, Mienert J, Romswinkel E, Morellini F, Ferrer I, Nicolini C, Fahnestock M, Rune G, Glatzel M, Galliciotti G. Reumann R, et al. Among authors: morellini f. Learn Mem. 2017 Nov 15;24(12):650-659. doi: 10.1101/lm.045864.117. Print 2017 Dec. Learn Mem. 2017. PMID: 29142062 Free PMC article.
Altered TAOK2 activity causes autism-related neurodevelopmental and cognitive abnormalities through RhoA signaling.
Richter M, Murtaza N, Scharrenberg R, White SH, Johanns O, Walker S, Yuen RKC, Schwanke B, Bedürftig B, Henis M, Scharf S, Kraus V, Dörk R, Hellmann J, Lindenmaier Z, Ellegood J, Hartung H, Kwan V, Sedlacik J, Fiehler J, Schweizer M, Lerch JP, Hanganu-Opatz IL, Morellini F, Scherer SW, Singh KK, Calderon de Anda F. Richter M, et al. Among authors: morellini f. Mol Psychiatry. 2019 Sep;24(9):1329-1350. doi: 10.1038/s41380-018-0025-5. Epub 2018 Feb 21. Mol Psychiatry. 2019. PMID: 29467497 Free PMC article.
Male offspring born to mildly ZIKV-infected mice are at risk of developing neurocognitive disorders in adulthood.
Stanelle-Bertram S, Walendy-Gnirß K, Speiseder T, Thiele S, Asante IA, Dreier C, Kouassi NM, Preuß A, Pilnitz-Stolze G, Müller U, Thanisch S, Richter M, Scharrenberg R, Kraus V, Dörk R, Schau L, Herder V, Gerhauser I, Pfankuche VM, Käufer C, Waltl I, Moraes T, Sellau J, Hoenow S, Schmidt-Chanasit J, Jansen S, Schattling B, Ittrich H, Bartsch U, Renné T, Bartenschlager R, Arck P, Cadar D, Friese MA, Vapalahti O, Lotter H, Benites S, Rolling L, Gabriel M, Baumgärtner W, Morellini F, Hölter SM, Amarie O, Fuchs H, Hrabe de Angelis M, Löscher W, Calderon de Anda F, Gabriel G. Stanelle-Bertram S, et al. Among authors: morellini f. Nat Microbiol. 2018 Oct;3(10):1161-1174. doi: 10.1038/s41564-018-0236-1. Epub 2018 Sep 10. Nat Microbiol. 2018. PMID: 30202017
Ubiquitin C-terminal hydrolase L1 (UCH-L1) loss causes neurodegeneration by altering protein turnover in the first postnatal weeks.
Reinicke AT, Laban K, Sachs M, Kraus V, Walden M, Damme M, Sachs W, Reichelt J, Schweizer M, Janiesch PC, Duncan KE, Saftig P, Rinschen MM, Morellini F, Meyer-Schwesinger C. Reinicke AT, et al. Among authors: morellini f. Proc Natl Acad Sci U S A. 2019 Apr 16;116(16):7963-7972. doi: 10.1073/pnas.1812413116. Epub 2019 Mar 28. Proc Natl Acad Sci U S A. 2019. PMID: 30923110 Free PMC article.
Physiological relevance of the neuronal isoform of inositol-1,4,5-trisphosphate 3-kinases in mice.
Blechner C, Becker L, Fuchs H, Rathkolb B, Prehn C, Adler T, Calzada-Wack J, Garrett L, Gailus-Durner V, Morellini F, Conrad S, Hölter SM, Wolf E, Klopstock T, Adamski J, Busch D, de Angelis MH, Schmeisser MJ, Windhorst S. Blechner C, et al. Among authors: morellini f. Neurosci Lett. 2020 Sep 14;735:135206. doi: 10.1016/j.neulet.2020.135206. Epub 2020 Jun 25. Neurosci Lett. 2020. PMID: 32593773
48 results