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A selective CuII complex with 4-fluorophenoxyacetic acid hydrazide and phenanthroline displays DNA-cleaving and pro-apoptotic properties in cancer cells.
Machado PHA, Paixão DA, Lino RC, de Souza TR, de Souza Bontempo NJ, Sousa LM, Van Petten de Vasconcelos Azevedo F, Orsolin PC, Lima PMAP, Martins IC, da Costa Guerra JF, Teixeira SC, Araújo TG, Goulart LR, Morelli S, Guerra W, de Oliveira Júnior RJ. Machado PHA, et al. Among authors: morelli s. Sci Rep. 2021 Dec 27;11(1):24450. doi: 10.1038/s41598-021-03909-1. Sci Rep. 2021. PMID: 34961767 Free PMC article.
Action of copper(II) complex with β-diketone and 1,10-phenanthroline (CBP-01) on sarcoma cells and biological effects under cell death.
Polloni L, Seni Silva AC, Teixeira SC, Azevedo FVPV, Zóia MAP, da Silva MS, Lima PMAP, Correia LIV, do Couto Almeida J, da Silva CV, Rodrigues Ávila VM, Goulart LRF, Morelli S, Guerra W, Oliveira Júnior RJ. Polloni L, et al. Among authors: morelli s. Biomed Pharmacother. 2019 Apr;112:108586. doi: 10.1016/j.biopha.2019.01.047. Epub 2019 Feb 18. Biomed Pharmacother. 2019. PMID: 30784909 Free article.
In vitro and in vivo antitumoral activity of a ternary copper (II) complex.
Lopes JC, Botelho FV, Barbosa Silva MJ, Silva SF, Polloni L, Alves Machado PH, Rodrigues de Souza T, Goulart LR, Silva Caldeira PP, Pereira Maia EC, Morelli S, de Oliveira-Júnior RJ. Lopes JC, et al. Among authors: morelli s. Biochem Biophys Res Commun. 2020 Dec 17;533(4):1021-1026. doi: 10.1016/j.bbrc.2020.09.104. Epub 2020 Oct 2. Biochem Biophys Res Commun. 2020. PMID: 33012510 Free article.
440 results