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Blocking IL-10 signaling with soluble IL-10 receptor restores in vitro specific lymphoproliferative response in dogs with leishmaniasis caused by Leishmania infantum.
Santos CO, Costa SF, Souza FS, Mendes JMF, de Pinheiro CGM, Moreira DRM, Silva LK, de Lima VMF, de Sá Oliveira GG. Santos CO, et al. Among authors: moreira drm. PLoS One. 2021 Jan 19;16(1):e0239171. doi: 10.1371/journal.pone.0239171. eCollection 2021. PLoS One. 2021. PMID: 33465107 Free PMC article.
hERG, Plasmodium Life Cycle, and Cross Resistance Profiling of New Azabenzimidazole Analogues of Astemizole.
Mambwe D, Coertzen D, Leshabane M, Mulubwa M, Njoroge M, Gibhard L, Girling G, Wicht KJ, Lee MCS, Wittlin S, Moreira DRM, Birkholtz LM, Chibale K. Mambwe D, et al. Among authors: moreira drm. ACS Med Chem Lett. 2024 Mar 18;15(4):463-469. doi: 10.1021/acsmedchemlett.3c00496. eCollection 2024 Apr 11. ACS Med Chem Lett. 2024. PMID: 38628794 Free PMC article.
Autofluorescent antimalarials by hybridization of artemisinin and coumarin: in vitro/in vivo studies and live-cell imaging.
Herrmann L, Leidenberger M, Sacramento de Morais A, Mai C, Çapci A, da Cruz Borges Silva M, Plass F, Kahnt A, Moreira DRM, Kappes B, Tsogoeva SB. Herrmann L, et al. Among authors: moreira drm. Chem Sci. 2023 Oct 24;14(45):12941-12952. doi: 10.1039/d3sc03661h. eCollection 2023 Nov 22. Chem Sci. 2023. PMID: 38023498 Free PMC article.
Antimalarial Agents Derived from Metal-Amodiaquine Complexes with Activity in Multiple Stages of the Plasmodium Life Cycle.
Colina-Vegas L, da Cruz B Silva M, de Souza Pereira C, Isis Barros A, Araújo Nobrega J, Navarro M, Rottmann M, D'Alessandro S, Basilico N, Azevedo Batista A, Moreira DRM. Colina-Vegas L, et al. Among authors: moreira drm. Chemistry. 2023 Oct 2;29(55):e202301642. doi: 10.1002/chem.202301642. Epub 2023 Aug 18. Chemistry. 2023. PMID: 37427863
A Hybrid of Amodiaquine and Primaquine Linked by Gold(I) Is a Multistage Antimalarial Agent Targeting Heme Detoxification and Thiol Redox Homeostasis.
De Souza Pereira C, Quadros HC, Aboagye SY, Fontinha D, D'Alessandro S, Byrne ME, Gendrot M, Fonta I, Mosnier J, Moreira DRM, Basilico N, Williams DL, Prudêncio M, Pradines B, Navarro M. De Souza Pereira C, et al. Among authors: moreira drm. Pharmaceutics. 2022 Jun 12;14(6):1251. doi: 10.3390/pharmaceutics14061251. Pharmaceutics. 2022. PMID: 35745823 Free PMC article.
67 results