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Arylpiperazinylalkyl derivatives of 8-amino-1,3-dimethylpurine-2,6-dione as novel multitarget 5-HT/D receptor agents with potential antipsychotic activity.
Chłoń-Rzepa G, Bucki A, Kołaczkowski M, Partyka A, Jastrzębska-Więsek M, Satała G, Bojarski AJ, Kalinowska-Tłuścik J, Kazek G, Mordyl B, Głuch-Lutwin M, Wesołowska A. Chłoń-Rzepa G, et al. Among authors: mordyl b. J Enzyme Inhib Med Chem. 2016 Dec;31(6):1048-62. doi: 10.3109/14756366.2015.1088844. Epub 2015 Sep 25. J Enzyme Inhib Med Chem. 2016. PMID: 26406608
Antidepressant- and Anxiolytic-Like Effects of New Dual 5-HT₁A and 5-HT₇ Antagonists in Animal Models.
Pytka K, Partyka A, Jastrzębska-Więsek M, Siwek A, Głuch-Lutwin M, Mordyl B, Kazek G, Rapacz A, Olczyk A, Gałuszka A, Błachuta M, Waszkielewicz A, Marona H, Sapa J, Filipek B, Wesołowska A. Pytka K, et al. Among authors: mordyl b. PLoS One. 2015 Nov 10;10(11):e0142499. doi: 10.1371/journal.pone.0142499. eCollection 2015. PLoS One. 2015. PMID: 26554929 Free PMC article.
Design, synthesis, and biological evaluation of fluorinated imidazo[1,2-a]pyridine derivatives with potential antipsychotic activity.
Marcinkowska M, Kołaczkowski M, Kamiński K, Bucki A, Pawłowski M, Siwek A, Karcz T, Mordyl B, Starowicz G, Kubowicz P, Pękala E, Wesołowska A, Samochowiec J, Mierzejewski P, Bienkowski P. Marcinkowska M, et al. Among authors: mordyl b. Eur J Med Chem. 2016 Nov 29;124:456-467. doi: 10.1016/j.ejmech.2016.08.059. Epub 2016 Aug 26. Eur J Med Chem. 2016. PMID: 27598234
Molecular mechanism of action and safety of 5-(3-chlorophenyl)-4-hexyl-2,4-dihydro-3H-1,2,4-triazole-3-thione - a novel anticonvulsant drug candidate.
Kaproń B, Łuszczki J, Paneth A, Wujec M, Siwek A, Karcz T, Mordyl B, Głuch-Lutwin M, Gryboś A, Nowak G, Pająk K, Jóźwiak K, Tomczykowski A, Plech T. Kaproń B, et al. Among authors: mordyl b. Int J Med Sci. 2017 Jul 18;14(8):741-749. doi: 10.7150/ijms.20001. eCollection 2017. Int J Med Sci. 2017. PMID: 28824309 Free PMC article.
34 results