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2-(4-Fluorophenyl)-1H-benzo[d]imidazole as a Promising Template for the Development of Metabolically Robust, α1β2γ2GABA-A Receptor-Positive Allosteric Modulators.
Marcinkowska M, Fajkis-Zajączkowska N, Szafrańska K, Jończyk J, Siwek A, Mordyl B, Karcz T, Latacz G, Kolaczkowski M. Marcinkowska M, et al. Among authors: mordyl b. ACS Chem Neurosci. 2023 Mar 15;14(6):1166-1180. doi: 10.1021/acschemneuro.2c00800. Epub 2023 Feb 27. ACS Chem Neurosci. 2023. PMID: 36848624 Free PMC article.
Arylpiperazinylalkyl derivatives of 8-amino-1,3-dimethylpurine-2,6-dione as novel multitarget 5-HT/D receptor agents with potential antipsychotic activity.
Chłoń-Rzepa G, Bucki A, Kołaczkowski M, Partyka A, Jastrzębska-Więsek M, Satała G, Bojarski AJ, Kalinowska-Tłuścik J, Kazek G, Mordyl B, Głuch-Lutwin M, Wesołowska A. Chłoń-Rzepa G, et al. Among authors: mordyl b. J Enzyme Inhib Med Chem. 2016 Dec;31(6):1048-62. doi: 10.3109/14756366.2015.1088844. Epub 2015 Sep 25. J Enzyme Inhib Med Chem. 2016. PMID: 26406608
Antidepressant- and Anxiolytic-Like Effects of New Dual 5-HT₁A and 5-HT₇ Antagonists in Animal Models.
Pytka K, Partyka A, Jastrzębska-Więsek M, Siwek A, Głuch-Lutwin M, Mordyl B, Kazek G, Rapacz A, Olczyk A, Gałuszka A, Błachuta M, Waszkielewicz A, Marona H, Sapa J, Filipek B, Wesołowska A. Pytka K, et al. Among authors: mordyl b. PLoS One. 2015 Nov 10;10(11):e0142499. doi: 10.1371/journal.pone.0142499. eCollection 2015. PLoS One. 2015. PMID: 26554929 Free PMC article.
Design, synthesis, and biological evaluation of fluorinated imidazo[1,2-a]pyridine derivatives with potential antipsychotic activity.
Marcinkowska M, Kołaczkowski M, Kamiński K, Bucki A, Pawłowski M, Siwek A, Karcz T, Mordyl B, Starowicz G, Kubowicz P, Pękala E, Wesołowska A, Samochowiec J, Mierzejewski P, Bienkowski P. Marcinkowska M, et al. Among authors: mordyl b. Eur J Med Chem. 2016 Nov 29;124:456-467. doi: 10.1016/j.ejmech.2016.08.059. Epub 2016 Aug 26. Eur J Med Chem. 2016. PMID: 27598234
Molecular mechanism of action and safety of 5-(3-chlorophenyl)-4-hexyl-2,4-dihydro-3H-1,2,4-triazole-3-thione - a novel anticonvulsant drug candidate.
Kaproń B, Łuszczki J, Paneth A, Wujec M, Siwek A, Karcz T, Mordyl B, Głuch-Lutwin M, Gryboś A, Nowak G, Pająk K, Jóźwiak K, Tomczykowski A, Plech T. Kaproń B, et al. Among authors: mordyl b. Int J Med Sci. 2017 Jul 18;14(8):741-749. doi: 10.7150/ijms.20001. eCollection 2017. Int J Med Sci. 2017. PMID: 28824309 Free PMC article.
Synthesis and computer-aided SAR studies for derivatives of phenoxyalkyl-1,3,5-triazine as the new potent ligands for serotonin receptors 5-HT6.
Ali W, Więcek M, Łażewska D, Kurczab R, Jastrzębska-Więsek M, Satała G, Kucwaj-Brysz K, Lubelska A, Głuch-Lutwin M, Mordyl B, Siwek A, Nasim MJ, Partyka A, Sudoł S, Latacz G, Wesołowska A, Kieć-Kononowicz K, Handzlik J. Ali W, et al. Among authors: mordyl b. Eur J Med Chem. 2019 Sep 15;178:740-751. doi: 10.1016/j.ejmech.2019.06.022. Epub 2019 Jun 10. Eur J Med Chem. 2019. PMID: 31229876
New Dual Small Molecules for Alzheimer's Disease Therapy Combining Histamine H3 Receptor (H3R) Antagonism and Calcium Channels Blockade with Additional Cholinesterase Inhibition.
Malek R, Arribas RL, Palomino-Antolin A, Totoson P, Demougeot C, Kobrlova T, Soukup O, Iriepa I, Moraleda I, Diez-Iriepa D, Godyń J, Panek D, Malawska B, Głuch-Lutwin M, Mordyl B, Siwek A, Chabchoub F, Marco-Contelles J, Kiec-Kononowicz K, Egea J, de Los Ríos C, Ismaili L. Malek R, et al. Among authors: mordyl b. J Med Chem. 2019 Dec 26;62(24):11416-11422. doi: 10.1021/acs.jmedchem.9b00937. Epub 2019 Dec 5. J Med Chem. 2019. PMID: 31724859
34 results