Mordhorst S - Search Results

1

Structural and Biochemical Insights into Post-Translational Arginine-to-Ornithine Peptide Modifications by an Atypical Arginase.

Mordhorst S, Badmann T, Bösch NM, Morinaka BI, Rauch H, Piel J, Groll M, Vagstad AL. Mordhorst S, et al. ACS Chem Biol. 2023 Mar 17;18(3):528-536. doi: 10.1021/acschembio.2c00879. Epub 2023 Feb 15. ACS Chem Biol. 2023. PMID: 36791048 Free PMC article.

2

Posttranslationally Acting Arginases Provide a Ribosomal Route to Non-proteinogenic Ornithine Residues in Diverse Peptide Sequences.

Mordhorst S, Morinaka BI, Vagstad AL, Piel J. Mordhorst S, et al. Angew Chem Int Ed Engl. 2020 Nov 23;59(48):21442-21447. doi: 10.1002/anie.202008990. Epub 2020 Sep 17. Angew Chem Int Ed Engl. 2020. PMID: 32780902

3

Emulating nonribosomal peptides with ribosomal biosynthetic strategies.

Mordhorst S, Ruijne F, Vagstad AL, Kuipers OP, Piel J. Mordhorst S, et al. RSC Chem Biol. 2022 Dec 6;4(1):7-36. doi: 10.1039/d2cb00169a. eCollection 2023 Jan 4. RSC Chem Biol. 2022. PMID: 36685251 Free PMC article. Review.

4

Round, round we go - strategies for enzymatic cofactor regeneration.

Mordhorst S, Andexer JN. Mordhorst S, et al. Nat Prod Rep. 2020 Oct 1;37(10):1316-1333. doi: 10.1039/d0np00004c. Epub 2020 Jun 25. Nat Prod Rep. 2020. PMID: 32582886 Review.

5

Several Polyphosphate Kinase 2 Enzymes Catalyse the Production of Adenosine 5'-Polyphosphates.

Mordhorst S, Singh J, Mohr MKF, Hinkelmann R, Keppler M, Jessen HJ, Andexer JN. Mordhorst S, et al. Chembiochem. 2019 Apr 15;20(8):1019-1022. doi: 10.1002/cbic.201800704. Epub 2019 Feb 28. Chembiochem. 2019. PMID: 30549179

6

A bicyclic S-adenosylmethionine regeneration system applicable with different nucleosides or nucleotides as cofactor building blocks.

Popadić D, Mhaindarkar D, Dang Thai MHN, Hailes HC, Mordhorst S, Andexer JN. Popadić D, et al. Among authors: mordhorst s. RSC Chem Biol. 2021 Mar 22;2(3):883-891. doi: 10.1039/d1cb00033k. RSC Chem Biol. 2021. PMID: 34179784 Free PMC article.

7

Substrate recognition and mechanism revealed by ligand-bound polyphosphate kinase 2 structures.

Parnell AE, Mordhorst S, Kemper F, Giurrandino M, Prince JP, Schwarzer NJ, Hofer A, Wohlwend D, Jessen HJ, Gerhardt S, Einsle O, Oyston PCF, Andexer JN, Roach PL. Parnell AE, et al. Among authors: mordhorst s. Proc Natl Acad Sci U S A. 2018 Mar 27;115(13):3350-3355. doi: 10.1073/pnas.1710741115. Epub 2018 Mar 12. Proc Natl Acad Sci U S A. 2018. PMID: 29531036 Free PMC article.

8

Opportunities and challenges of RiPP-based therapeutics.

Pfeiffer IP, Schröder MP, Mordhorst S. Pfeiffer IP, et al. Among authors: mordhorst s. Nat Prod Rep. 2024 Feb 27. doi: 10.1039/d3np00057e. Online ahead of print. Nat Prod Rep. 2024. PMID: 38411278 Review.

9

Biomimetic S-Adenosylmethionine Regeneration Starting from Multiple Byproducts Enables Biocatalytic Alkylation with Radical SAM Enzymes.

Gericke L, Mhaindarkar D, Karst LC, Jahn S, Kuge M, Mohr MKF, Gagsteiger J, Cornelissen NV, Wen X, Mordhorst S, Jessen HJ, Rentmeister A, Seebeck FP, Layer G, Loenarz C, Andexer JN. Gericke L, et al. Among authors: mordhorst s. Chembiochem. 2023 May 2;24(9):e202300133. doi: 10.1002/cbic.202300133. Epub 2023 Apr 4. Chembiochem. 2023. PMID: 36942622

10

Chorismatases - the family is growing.

Grüninger MJ , Buchholz PCF , Mordhorst S , Strack P , Müller M , Hubrich F , Pleiss J , Andexer JN . Grüninger MJ , et al. Among authors: mordhorst s. Org Biomol Chem. 2019 Feb 20;17(8):2092-2098. doi: 10.1039/c8ob03038c. Org Biomol Chem. 2019. PMID: 30706936

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