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Transmembrane domain-driven PD-1 dimers mediate T cell inhibition.
Philips EA, Liu J, Kvalvaag A, Mørch AM, Tocheva AS, Ng C, Liang H, Ahearn IM, Pan R, Luo CC, Leithner A, Qin Z, Zhou Y, Garcia-España A, Mor A, Littman DR, Dustin ML, Wang J, Kong XP. Philips EA, et al. Among authors: morch am. Sci Immunol. 2024 Mar 8;9(93):eade6256. doi: 10.1126/sciimmunol.ade6256. Epub 2024 Mar 8. Sci Immunol. 2024. PMID: 38457513
Using CombiCells, a platform for titration and combinatorial display of cell surface ligands, to study T-cell antigen sensitivity modulation by accessory receptors.
Patel A, Andre V, Eguiguren SB, Barton MI, Burton J, Denham EM, Pettmann J, Mørch AM, Kutuzov MA, Siller-Farfán JA, Dustin ML, van der Merwe PA, Dushek O. Patel A, et al. Among authors: morch am. EMBO J. 2024 Jan;43(1):132-150. doi: 10.1038/s44318-023-00012-1. Epub 2023 Dec 18. EMBO J. 2024. PMID: 38177315 Free PMC article.
Curving out a new path: CD28/B7 cis interactions.
Zhou XMM, Mørch AM, Dustin ML. Zhou XMM, et al. Among authors: morch am. Immunity. 2023 Jun 13;56(6):1155-1157. doi: 10.1016/j.immuni.2023.05.002. Immunity. 2023. PMID: 37315528
The kinase occupancy of T cell coreceptors reconsidered.
Mørch AM, Schneider F, Jenkins E, Santos AM, Fraser SE, Davis SJ, Dustin ML. Mørch AM, et al. Proc Natl Acad Sci U S A. 2022 Dec 6;119(49):e2213538119. doi: 10.1073/pnas.2213538119. Epub 2022 Dec 1. Proc Natl Acad Sci U S A. 2022. PMID: 36454761 Free PMC article.
Coreceptors and TCR Signaling - the Strong and the Weak of It.
Mørch AM, Bálint Š, Santos AM, Davis SJ, Dustin ML. Mørch AM, et al. Front Cell Dev Biol. 2020 Oct 16;8:597627. doi: 10.3389/fcell.2020.597627. eCollection 2020. Front Cell Dev Biol. 2020. PMID: 33178706 Free PMC article. Review.
Structural basis for RIFIN-mediated activation of LILRB1 in malaria.
Harrison TE, Mørch AM, Felce JH, Sakoguchi A, Reid AJ, Arase H, Dustin ML, Higgins MK. Harrison TE, et al. Among authors: morch am. Nature. 2020 Nov;587(7833):309-312. doi: 10.1038/s41586-020-2530-3. Epub 2020 Jul 10. Nature. 2020. PMID: 32650338 Free PMC article.
17 results