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Fused Enzyme Glucose-6-Phosphate Dehydrogenase::6-Phosphogluconolactonase (G6PD::6PGL) as a Potential Drug Target in Giardia lamblia, Trichomonas vaginalis, and Plasmodium falciparum.
Morales-Luna L, Vázquez-Bautista M, Martínez-Rosas V, Rojas-Alarcón MA, Ortega-Cuellar D, González-Valdez A, Pérez de la Cruz V, Arreguin-Espinosa R, Rodríguez-Bustamante E, Rodríguez-Flores E, Hernández-Ochoa B, Gómez-Manzo S. Morales-Luna L, et al. Microorganisms. 2024 Jan 5;12(1):112. doi: 10.3390/microorganisms12010112. Microorganisms. 2024. PMID: 38257939 Free PMC article. Review.
An Overall View of the Functional and Structural Characterization of Glucose-6-Phosphate Dehydrogenase Variants in the Mexican Population.
Hernández-Ochoa B, Ortega-Cuellar D, González-Valdez A, Martínez-Rosas V, Morales-Luna L, Rojas-Alarcón MA, Vázquez-Bautista M, Arreguin-Espinosa R, Pérez de la Cruz V, Castillo-Rodríguez RA, Canseco-Ávila LM, Vidal-Limón A, Gómez-Manzo S. Hernández-Ochoa B, et al. Among authors: morales luna l. Int J Mol Sci. 2023 Aug 11;24(16):12691. doi: 10.3390/ijms241612691. Int J Mol Sci. 2023. PMID: 37628871 Free PMC article. Review.
Nitazoxanide Inhibits the Bifunctional Enzyme GlG6PD::6PGL of Giardia lamblia: Biochemical and In Silico Characterization of a New Druggable Target.
Martínez-Rosas V, Hernández-Ochoa B, Morales-Luna L, Ortega-Cuellar D, González-Valdez A, Arreguin-Espinosa R, Rufino-González Y, Calderón-Jaimes E, Castillo-Rodríguez RA, Wong-Baeza C, Baeza-Ramírez I, Pérez de la Cruz V, Vidal-Limón A, Gómez-Manzo S. Martínez-Rosas V, et al. Among authors: morales luna l. Int J Mol Sci. 2023 Jul 15;24(14):11516. doi: 10.3390/ijms241411516. Int J Mol Sci. 2023. PMID: 37511272 Free PMC article.
Pyridyl Methylsulfinyl Benzimidazole Derivatives as Promising Agents against Giardia lamblia and Trichomonas vaginalis.
Hernández-Ochoa B, Martínez-Rosas V, Morales-Luna L, Calderón-Jaimes E, Rocha-Ramírez LM, Ortega-Cuellar D, Rufino-González Y, González-Valdez A, Arreguin-Espinosa R, Enríquez-Flores S, Castillo-Rodríguez RA, Cárdenas-Rodríguez N, Wong-Baeza C, Baeza-Ramírez I, Gómez-Manzo S. Hernández-Ochoa B, et al. Among authors: morales luna l. Molecules. 2022 Dec 14;27(24):8902. doi: 10.3390/molecules27248902. Molecules. 2022. PMID: 36558035 Free PMC article.
Giardia lamblia G6PD::6PGL Fused Protein Inhibitors Decrease Trophozoite Viability: A New Alternative against Giardiasis.
Morales-Luna L, Hernández-Ochoa B, Martínez-Rosas V, Navarrete-Vázquez G, Ortega-Cuellar D, Rufino-González Y, González-Valdez A, Arreguin-Espinosa R, Franco-Vásquez AM, Pérez de la Cruz V, Enríquez-Flores S, Martínez-Conde C, Canseco-Ávila LM, Gómez-Chávez F, Gómez-Manzo S. Morales-Luna L, et al. Int J Mol Sci. 2022 Nov 18;23(22):14358. doi: 10.3390/ijms232214358. Int J Mol Sci. 2022. PMID: 36430836 Free PMC article.
Biochemical and Kinetic Characterization of the Glucose-6-Phosphate Dehydrogenase from Helicobacter pylori Strain 29CaP.
Ortiz-Ramírez P, Hernández-Ochoa B, Ortega-Cuellar D, González-Valdez A, Martínez-Rosas V, Morales-Luna L, Arreguin-Espinosa R, Castillo-Rodríguez RA, Canseco-Ávila LM, Cárdenas-Rodríguez N, Pérez de la Cruz V, Montiel-González AM, Gómez-Chávez F, Gómez-Manzo S. Ortiz-Ramírez P, et al. Among authors: morales luna l. Microorganisms. 2022 Jul 6;10(7):1359. doi: 10.3390/microorganisms10071359. Microorganisms. 2022. PMID: 35889079 Free PMC article.
Kinetic and Molecular Docking Studies to Determine the Effect of Inhibitors on the Activity and Structure of Fused G6PD::6PGL Protein from Trichomonas vaginalis.
Martínez-Rosas V, Hernández-Ochoa B, Navarrete-Vázquez G, Martínez-Conde C, Gómez-Chávez F, Morales-Luna L, González-Valdez A, Arreguin-Espinosa R, Enríquez-Flores S, Pérez de la Cruz V, Aguayo-Ortiz R, Wong-Baeza C, Baeza-Ramírez I, Gómez-Manzo S. Martínez-Rosas V, et al. Among authors: morales luna l. Molecules. 2022 Feb 9;27(4):1174. doi: 10.3390/molecules27041174. Molecules. 2022. PMID: 35208965 Free PMC article.
Validation and Selection of New Reference Genes for RT-qPCR Analysis in Pediatric Glioma of Different Grades.
Hernández-Ochoa B, Fernández-Rosario F, Castillo-Rodríguez RA, Marhx-Bracho A, Cárdenas-Rodríguez N, Martínez-Rosas V, Morales-Luna L, González-Valdez A, Calderón-Jaimes E, Pérez de la Cruz V, Rivera-Gutiérrez S, Meza-Toledo S, Wong-Baeza C, Baeza-Ramírez I, Gómez-Manzo S. Hernández-Ochoa B, et al. Among authors: morales luna l. Genes (Basel). 2021 Aug 27;12(9):1335. doi: 10.3390/genes12091335. Genes (Basel). 2021. PMID: 34573317 Free PMC article.
Identification and In Silico Characterization of Novel Helicobacter pylori Glucose-6-Phosphate Dehydrogenase Inhibitors.
Hernández-Ochoa B, Navarrete-Vázquez G, Aguayo-Ortiz R, Ortiz-Ramírez P, Morales-Luna L, Martínez-Rosas V, González-Valdez A, Gómez-Chávez F, Enríquez-Flores S, Wong-Baeza C, Baeza-Ramírez I, Pérez de la Cruz V, Gómez-Manzo S. Hernández-Ochoa B, et al. Among authors: morales luna l. Molecules. 2021 Aug 16;26(16):4955. doi: 10.3390/molecules26164955. Molecules. 2021. PMID: 34443540 Free PMC article.
Glucose-6-Phosphate Dehydrogenase::6-Phosphogluconolactonase from the Parasite Giardia lamblia. A Molecular and Biochemical Perspective of a Fused Enzyme.
Morales-Luna L, González-Valdez A, Hernández-Ochoa B, Arreguin-Espinosa R, Ortega-Cuellar D, Castillo-Rodríguez RA, Martínez-Rosas V, Cárdenas-Rodríguez N, Enríquez-Flores S, Canseco-Ávila LM, Cruz VP, Gómez-Chávez F, Gómez-Manzo S. Morales-Luna L, et al. Microorganisms. 2021 Aug 7;9(8):1678. doi: 10.3390/microorganisms9081678. Microorganisms. 2021. PMID: 34442758 Free PMC article.
17 results