Morales P - Search Results

1

An Update on Non-CB₁, Non-CB₂ Cannabinoid Related G-Protein-Coupled Receptors.

Morales P, Reggio PH. Morales P, et al. Cannabis Cannabinoid Res. 2017 Oct 1;2(1):265-273. doi: 10.1089/can.2017.0036. eCollection 2017. Cannabis Cannabinoid Res. 2017. PMID: 29098189 Free PMC article. Review.

2

Chromenopyrazoles: non-psychoactive and selective CB₁ cannabinoid agonists with peripheral antinociceptive properties.

Cumella J, Hernández-Folgado L, Girón R, Sánchez E, Morales P, Hurst DP, Gómez-Cañas M, Gómez-Ruiz M, Pinto DC, Goya P, Reggio PH, Martin MI, Fernández-Ruiz J, Silva AM, Jagerovic N. Cumella J, et al. Among authors: morales p. ChemMedChem. 2012 Mar 5;7(3):452-63. doi: 10.1002/cmdc.201100568. Epub 2012 Feb 2. ChemMedChem. 2012. PMID: 22302767 Free PMC article.

3

Synthesis, pharmacological evaluation and docking studies of pyrrole structure-based CB2 receptor antagonists.

Ragusa G, Gómez-Cañas M, Morales P, Hurst DP, Deligia F, Pazos R, Pinna GA, Fernández-Ruiz J, Goya P, Reggio PH, Jagerovic N, García-Arencibia M, Murineddu G. Ragusa G, et al. Among authors: morales p. Eur J Med Chem. 2015 Aug 28;101:651-67. doi: 10.1016/j.ejmech.2015.06.057. Epub 2015 Jul 15. Eur J Med Chem. 2015. PMID: 26209834

4

Chromenopyrazole, a Versatile Cannabinoid Scaffold with in Vivo Activity in a Model of Multiple Sclerosis.

Morales P, Gómez-Cañas M, Navarro G, Hurst DP, Carrillo-Salinas FJ, Lagartera L, Pazos R, Goya P, Reggio PH, Guaza C, Franco R, Fernández-Ruiz J, Jagerovic N. Morales P, et al. J Med Chem. 2016 Jul 28;59(14):6753-6771. doi: 10.1021/acs.jmedchem.6b00397. Epub 2016 Jul 6. J Med Chem. 2016. PMID: 27309150 Free PMC article.

5

Molecular Targets of the Phytocannabinoids: A Complex Picture.

Morales P, Hurst DP, Reggio PH. Morales P, et al. Prog Chem Org Nat Prod. 2017;103:103-131. doi: 10.1007/978-3-319-45541-9_4. Prog Chem Org Nat Prod. 2017. PMID: 28120232 Free PMC article. Review.

6

An Overview on Medicinal Chemistry of Synthetic and Natural Derivatives of Cannabidiol.

Morales P, Reggio PH, Jagerovic N. Morales P, et al. Front Pharmacol. 2017 Jun 28;8:422. doi: 10.3389/fphar.2017.00422. eCollection 2017. Front Pharmacol. 2017. PMID: 28701957 Free PMC article. Review.

7

Methods for the Development of In Silico GPCR Models.

Morales P, Hurst DP, Reggio PH. Morales P, et al. Methods Enzymol. 2017;593:405-448. doi: 10.1016/bs.mie.2017.05.005. Epub 2017 Jul 14. Methods Enzymol. 2017. PMID: 28750813 Free PMC article.

8

Towards a better understanding of the cannabinoid-related orphan receptors GPR3, GPR6, and GPR12.

Morales P, Isawi I, Reggio PH. Morales P, et al. Drug Metab Rev. 2018 Feb;50(1):74-93. doi: 10.1080/03602532.2018.1428616. Epub 2018 Feb 1. Drug Metab Rev. 2018. PMID: 29390908 Free PMC article. Review.

9

Synthesis, Pharmacological Evaluation, and Docking Studies of Novel Pyridazinone-Based Cannabinoid Receptor Type 2 Ligands.

Ragusa G, Bencivenni S, Morales P, Callaway T, Hurst DP, Asproni B, Merighi S, Loriga G, Pinna GA, Reggio PH, Gessi S, Murineddu G. Ragusa G, et al. Among authors: morales p. ChemMedChem. 2018 Jun 6;13(11):1102-1114. doi: 10.1002/cmdc.201800152. Epub 2018 Apr 16. ChemMedChem. 2018. PMID: 29575721

10

( R)- N-(1-Methyl-2-hydroxyethyl)-13-( S)-methyl-arachidonamide (AMG315): A Novel Chiral Potent Endocannabinoid Ligand with Stability to Metabolizing Enzymes.

Liu Y, Ji L, Eno M, Kudalkar S, Li AL, Schimpgen M, Benchama O, Morales P, Xu S, Hurst D, Wu S, Mohammad KA, Wood JT, Zvonok N, Papahatjis DP, Zhou H, Honrao C, Mackie K, Reggio P, Hohmann AG, Marnett LJ, Makriyannis A, Nikas SP. Liu Y, et al. Among authors: morales p. J Med Chem. 2018 Oct 11;61(19):8639-8657. doi: 10.1021/acs.jmedchem.8b00611. Epub 2018 Sep 21. J Med Chem. 2018. PMID: 30196704

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