Moraes CB - Search Results

1

A potential antiviral against COVID-19 obtained from Byrsonima coccolobifolia leaves extract.

Rodrigues CM, Bento CC, Moraes CB, Gomes C, Ioshino RS, Freitas-Junior LH, de Castro Spadari C, Ishida K, Vilegas W, Carvalho JCS, Ferreira MJP, Carbone V, Piacente S, Molina de Angelo R, Honorio KM, Sannomiya M. Rodrigues CM, et al. Among authors: moraes cb. Fitoterapia. 2024 Mar;173:105820. doi: 10.1016/j.fitote.2024.105820. Epub 2024 Jan 9. Fitoterapia. 2024. PMID: 38211642

2

An image-based algorithm for precise and accurate high throughput assessment of drug activity against the human parasite Trypanosoma cruzi.

Moon S, Siqueira-Neto JL, Moraes CB, Yang G, Kang M, Freitas-Junior LH, Hansen MA. Moon S, et al. Among authors: moraes cb. PLoS One. 2014 Feb 4;9(2):e87188. doi: 10.1371/journal.pone.0087188. eCollection 2014. PLoS One. 2014. PMID: 24503652 Free PMC article.

3

Drug discovery for human African trypanosomiasis: identification of novel scaffolds by the newly developed HTS SYBR Green assay for Trypanosoma brucei.

Faria J, Moraes CB, Song R, Pascoalino BS, Lee N, Siqueira-Neto JL, Cruz DJ, Parkinson T, Ioset JR, Cordeiro-da-Silva A, Freitas-Junior LH. Faria J, et al. Among authors: moraes cb. J Biomol Screen. 2015 Jan;20(1):70-81. doi: 10.1177/1087057114556236. Epub 2014 Oct 23. J Biomol Screen. 2015. PMID: 25342146

4

Design, synthesis and antitrypanosomal activity of some nitrofurazone 1,2,4-triazolic bioisosteric analogues.

Silva FT, Franco CH, Favaro DC, Freitas-Junior LH, Moraes CB, Ferreira EI. Silva FT, et al. Among authors: moraes cb. Eur J Med Chem. 2016 Oct 4;121:553-560. doi: 10.1016/j.ejmech.2016.04.065. Epub 2016 Jun 1. Eur J Med Chem. 2016. PMID: 27318979

5

Synthesis and trypanocidal activity of a library of 4-substituted 2-(1H-pyrrolo[3,2-c]pyridin-2-yl)propan-2-ols.

Balfour MN, Franco CH, Moraes CB, Freitas-Junior LH, Stefani HA. Balfour MN, et al. Among authors: moraes cb. Eur J Med Chem. 2017 Mar 10;128:202-212. doi: 10.1016/j.ejmech.2017.01.040. Epub 2017 Feb 3. Eur J Med Chem. 2017. PMID: 28189084

6

Computer-aided discovery of two novel chalcone-like compounds active and selective against Leishmania infantum.

Gomes MN, Alcântara LM, Neves BJ, Melo-Filho CC, Freitas-Junior LH, Moraes CB, Ma R, Franzblau SG, Muratov E, Andrade CH. Gomes MN, et al. Among authors: moraes cb. Bioorg Med Chem Lett. 2017 Jun 1;27(11):2459-2464. doi: 10.1016/j.bmcl.2017.04.010. Epub 2017 Apr 4. Bioorg Med Chem Lett. 2017. PMID: 28434763 Free PMC article.

7

A comparative study of warheads for design of cysteine protease inhibitors.

Silva DG, Ribeiro JFR, De Vita D, Cianni L, Franco CH, Freitas-Junior LH, Moraes CB, Rocha JR, Burtoloso ACB, Kenny PW, Leitão A, Montanari CA. Silva DG, et al. Among authors: moraes cb. Bioorg Med Chem Lett. 2017 Nov 15;27(22):5031-5035. doi: 10.1016/j.bmcl.2017.10.002. Epub 2017 Oct 3. Bioorg Med Chem Lett. 2017. PMID: 29054358

8

Discovery of new potent hits against intracellular Trypanosoma cruzi by QSAR-based virtual screening.

Melo-Filho CC, Braga RC, Muratov EN, Franco CH, Moraes CB, Freitas-Junior LH, Andrade CH. Melo-Filho CC, et al. Among authors: moraes cb. Eur J Med Chem. 2019 Feb 1;163:649-659. doi: 10.1016/j.ejmech.2018.11.062. Epub 2018 Nov 29. Eur J Med Chem. 2019. PMID: 30562700

9

Drug Discovery for Chagas Disease: Impact of Different Host Cell Lines on Assay Performance and Hit Compound Selection.

Franco CH, Alcântara LM, Chatelain E, Freitas-Junior L, Moraes CB. Franco CH, et al. Among authors: moraes cb. Trop Med Infect Dis. 2019 May 17;4(2):82. doi: 10.3390/tropicalmed4020082. Trop Med Infect Dis. 2019. PMID: 31108888 Free PMC article.

10

Expanding the Biological Application of Fluorescent Benzothiadiazole Derivatives: A Phenotypic Screening Strategy for Anthelmintic Drug Discovery Using Caenorhabditis elegans.

Cintra GAS, Neto BAD, Carvalho PHPR, Moraes CB, Freitas-Junior LH. Cintra GAS, et al. Among authors: moraes cb. SLAS Discov. 2019 Aug;24(7):755-765. doi: 10.1177/2472555219851130. Epub 2019 Jun 10. SLAS Discov. 2019. PMID: 31180789 Free article.

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