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Disruption of the Ah receptor gene alters the susceptibility of mice to oxygen-mediated regulation of pulmonary and hepatic cytochromes P4501A expression and exacerbates hyperoxic lung injury.
Jiang W, Welty SE, Couroucli XI, Barrios R, Kondraganti SR, Muthiah K, Yu L, Avery SE, Moorthy B. Jiang W, et al. Among authors: moorthy b. J Pharmacol Exp Ther. 2004 Aug;310(2):512-9. doi: 10.1124/jpet.103.059766. Epub 2004 May 3. J Pharmacol Exp Ther. 2004. PMID: 15123765
Induction of CYP1A1 and CYP1B1 in liver and lung by benzo(a)pyrene and 7,12-d imethylbenz(a)anthracene do not affect distribution of polycyclic hydrocarbons to target tissue: role of AhR and CYP1B1 in bone marrow cytotoxicity.
Galván N, Teske DE, Zhou G, Moorthy B, MacWilliams PS, Czuprynski CJ, Jefcoate CR. Galván N, et al. Among authors: moorthy b. Toxicol Appl Pharmacol. 2005 Feb 1;202(3):244-57. doi: 10.1016/j.taap.2004.06.026. Toxicol Appl Pharmacol. 2005. PMID: 15667830
180 results