Moore J - Search Results

1

X-ray crystal structure of the liver X receptor beta ligand binding domain: regulation by a histidine-tryptophan switch.

Williams S, Bledsoe RK, Collins JL, Boggs S, Lambert MH, Miller AB, Moore J, McKee DD, Moore L, Nichols J, Parks D, Watson M, Wisely B, Willson TM. Williams S, et al. Among authors: moore j, moore l. J Biol Chem. 2003 Jul 18;278(29):27138-43. doi: 10.1074/jbc.M302260200. Epub 2003 May 7. J Biol Chem. 2003. PMID: 12736258 Free article.

2

Genomics versus orphan nuclear receptors--a half-time report.

Willson TM, Moore JT. Willson TM, et al. Mol Endocrinol. 2002 Jun;16(6):1135-44. doi: 10.1210/mend.16.6.0849. Mol Endocrinol. 2002. PMID: 12040002 Review.

3

Crystal structure of the glucocorticoid receptor ligand binding domain reveals a novel mode of receptor dimerization and coactivator recognition.

Bledsoe RK, Montana VG, Stanley TB, Delves CJ, Apolito CJ, McKee DD, Consler TG, Parks DJ, Stewart EL, Willson TM, Lambert MH, Moore JT, Pearce KH, Xu HE. Bledsoe RK, et al. Among authors: moore jt. Cell. 2002 Jul 12;110(1):93-105. doi: 10.1016/s0092-8674(02)00817-6. Cell. 2002. PMID: 12151000 Free article.

4

Identification of a novel human constitutive androstane receptor (CAR) agonist and its use in the identification of CAR target genes.

Maglich JM, Parks DJ, Moore LB, Collins JL, Goodwin B, Billin AN, Stoltz CA, Kliewer SA, Lambert MH, Willson TM, Moore JT. Maglich JM, et al. Among authors: moore lb, moore jt. J Biol Chem. 2003 May 9;278(19):17277-83. doi: 10.1074/jbc.M300138200. Epub 2003 Feb 27. J Biol Chem. 2003. PMID: 12611900 Free article.

5

A structural basis for constitutive activity in the human CAR/RXRalpha heterodimer.

Xu RX, Lambert MH, Wisely BB, Warren EN, Weinert EE, Waitt GM, Williams JD, Collins JL, Moore LB, Willson TM, Moore JT. Xu RX, et al. Mol Cell. 2004 Dec 22;16(6):919-28. doi: 10.1016/j.molcel.2004.11.042. Mol Cell. 2004. PMID: 15610735 Free article.

6

Structural determinants of ligand binding selectivity between the peroxisome proliferator-activated receptors.

Xu HE, Lambert MH, Montana VG, Plunket KD, Moore LB, Collins JL, Oplinger JA, Kliewer SA, Gampe RT Jr, McKee DD, Moore JT, Willson TM. Xu HE, et al. Among authors: moore lb, moore jt. Proc Natl Acad Sci U S A. 2001 Nov 20;98(24):13919-24. doi: 10.1073/pnas.241410198. Epub 2001 Nov 6. Proc Natl Acad Sci U S A. 2001. PMID: 11698662 Free PMC article.

7

Structural basis for antagonist-mediated recruitment of nuclear co-repressors by PPARalpha.

Xu HE, Stanley TB, Montana VG, Lambert MH, Shearer BG, Cobb JE, McKee DD, Galardi CM, Plunket KD, Nolte RT, Parks DJ, Moore JT, Kliewer SA, Willson TM, Stimmel JB. Xu HE, et al. Among authors: moore jt. Nature. 2002 Feb 14;415(6873):813-7. doi: 10.1038/415813a. Nature. 2002. PMID: 11845213

8

Pregnane X receptor (PXR), constitutive androstane receptor (CAR), and benzoate X receptor (BXR) define three pharmacologically distinct classes of nuclear receptors.

Moore LB, Maglich JM, McKee DD, Wisely B, Willson TM, Kliewer SA, Lambert MH, Moore JT. Moore LB, et al. Mol Endocrinol. 2002 May;16(5):977-86. doi: 10.1210/mend.16.5.0828. Mol Endocrinol. 2002. PMID: 11981033

9

Hepatocyte nuclear factor 4 is a transcription factor that constitutively binds fatty acids.

Wisely GB, Miller AB, Davis RG, Thornquest AD Jr, Johnson R, Spitzer T, Sefler A, Shearer B, Moore JT, Miller AB, Willson TM, Williams SP. Wisely GB, et al. Structure. 2002 Sep;10(9):1225-34. doi: 10.1016/s0969-2126(02)00829-8. Structure. 2002. PMID: 12220494 Free article.

10

Nuclear receptor regulation of genes involved in bile acid metabolism.

Moore JT, Goodwin B, Willson TM, Kliewer SA. Moore JT, et al. Crit Rev Eukaryot Gene Expr. 2002;12(2):119-35. doi: 10.1615/critreveukaryotgeneexpr.v12.i2.30. Crit Rev Eukaryot Gene Expr. 2002. PMID: 12434926 Review.

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