Moore DJ - Search Results

1

GTPase activity regulates kinase activity and cellular phenotypes of Parkinson's disease-associated LRRK2.

Biosa A, Trancikova A, Civiero L, Glauser L, Bubacco L, Greggio E, Moore DJ. Biosa A, et al. Among authors: moore dj. Hum Mol Genet. 2013 Mar 15;22(6):1140-56. doi: 10.1093/hmg/dds522. Epub 2012 Dec 13. Hum Mol Genet. 2013. PMID: 23241358

2

Parkinson's disease-associated mutations in LRRK2 link enhanced GTP-binding and kinase activities to neuronal toxicity.

West AB, Moore DJ, Choi C, Andrabi SA, Li X, Dikeman D, Biskup S, Zhang Z, Lim KL, Dawson VL, Dawson TM. West AB, et al. Among authors: moore dj. Hum Mol Genet. 2007 Jan 15;16(2):223-32. doi: 10.1093/hmg/ddl471. Epub 2007 Jan 2. Hum Mol Genet. 2007. PMID: 17200152

3

The chaperone activity of heat shock protein 90 is critical for maintaining the stability of leucine-rich repeat kinase 2.

Wang L, Xie C, Greggio E, Parisiadou L, Shim H, Sun L, Chandran J, Lin X, Lai C, Yang WJ, Moore DJ, Dawson TM, Dawson VL, Chiosis G, Cookson MR, Cai H. Wang L, et al. Among authors: moore dj. J Neurosci. 2008 Mar 26;28(13):3384-91. doi: 10.1523/JNEUROSCI.0185-08.2008. J Neurosci. 2008. PMID: 18367605 Free PMC article.

4

GTPase activity plays a key role in the pathobiology of LRRK2.

Xiong Y, Coombes CE, Kilaru A, Li X, Gitler AD, Bowers WJ, Dawson VL, Dawson TM, Moore DJ. Xiong Y, et al. Among authors: moore dj. PLoS Genet. 2010 Apr 8;6(4):e1000902. doi: 10.1371/journal.pgen.1000902. PLoS Genet. 2010. PMID: 20386743 Free PMC article.

5

A rat model of progressive nigral neurodegeneration induced by the Parkinson's disease-associated G2019S mutation in LRRK2.

Dusonchet J, Kochubey O, Stafa K, Young SM Jr, Zufferey R, Moore DJ, Schneider BL, Aebischer P. Dusonchet J, et al. Among authors: moore dj. J Neurosci. 2011 Jan 19;31(3):907-12. doi: 10.1523/JNEUROSCI.5092-10.2011. J Neurosci. 2011. PMID: 21248115 Free PMC article.

6

Genetic mouse models of neurodegenerative diseases.

Trancikova A, Ramonet D, Moore DJ. Trancikova A, et al. Among authors: moore dj. Prog Mol Biol Transl Sci. 2011;100:419-82. doi: 10.1016/B978-0-12-384878-9.00012-1. Prog Mol Biol Transl Sci. 2011. PMID: 21377633 Review.

7

Dopaminergic neuronal loss, reduced neurite complexity and autophagic abnormalities in transgenic mice expressing G2019S mutant LRRK2.

Ramonet D, Daher JP, Lin BM, Stafa K, Kim J, Banerjee R, Westerlund M, Pletnikova O, Glauser L, Yang L, Liu Y, Swing DA, Beal MF, Troncoso JC, McCaffery JM, Jenkins NA, Copeland NG, Galter D, Thomas B, Lee MK, Dawson TM, Dawson VL, Moore DJ. Ramonet D, et al. Among authors: moore dj. PLoS One. 2011 Apr 6;6(4):e18568. doi: 10.1371/journal.pone.0018568. PLoS One. 2011. PMID: 21494637 Free PMC article.

8

Parkin promotes the ubiquitination and degradation of the mitochondrial fusion factor mitofusin 1.

Glauser L, Sonnay S, Stafa K, Moore DJ. Glauser L, et al. Among authors: moore dj. J Neurochem. 2011 Aug;118(4):636-45. doi: 10.1111/j.1471-4159.2011.07318.x. Epub 2011 Jun 6. J Neurochem. 2011. PMID: 21615408 Free article.

9

Mitochondrial dysfunction in genetic animal models of Parkinson's disease.

Trancikova A, Tsika E, Moore DJ. Trancikova A, et al. Among authors: moore dj. Antioxid Redox Signal. 2012 May 1;16(9):896-919. doi: 10.1089/ars.2011.4200. Epub 2011 Oct 4. Antioxid Redox Signal. 2012. PMID: 21848447 Free PMC article. Review.

10

PARK9-associated ATP13A2 localizes to intracellular acidic vesicles and regulates cation homeostasis and neuronal integrity.

Ramonet D, Podhajska A, Stafa K, Sonnay S, Trancikova A, Tsika E, Pletnikova O, Troncoso JC, Glauser L, Moore DJ. Ramonet D, et al. Among authors: moore dj. Hum Mol Genet. 2012 Apr 15;21(8):1725-43. doi: 10.1093/hmg/ddr606. Epub 2011 Dec 20. Hum Mol Genet. 2012. PMID: 22186024 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

1,001 results

Search Page