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Multifactorial T-cell hypofunction that is reversible can limit the efficacy of chimeric antigen receptor-transduced human T cells in solid tumors.
Moon EK, Wang LC, Dolfi DV, Wilson CB, Ranganathan R, Sun J, Kapoor V, Scholler J, Puré E, Milone MC, June CH, Riley JL, Wherry EJ, Albelda SM. Moon EK, et al. Clin Cancer Res. 2014 Aug 15;20(16):4262-73. doi: 10.1158/1078-0432.CCR-13-2627. Epub 2014 Jun 11. Clin Cancer Res. 2014. PMID: 24919573 Free PMC article.
Immunotherapy: Beyond Anti-PD-1 and Anti-PD-L1 Therapies.
Antonia SJ, Vansteenkiste JF, Moon E. Antonia SJ, et al. Am Soc Clin Oncol Educ Book. 2016;35:e450-8. doi: 10.1200/EDBK_158712. Am Soc Clin Oncol Educ Book. 2016. PMID: 27249753 Free article. Review.
CAR T Cell Therapy for Solid Tumors.
Newick K, O'Brien S, Moon E, Albelda SM. Newick K, et al. Annu Rev Med. 2017 Jan 14;68:139-152. doi: 10.1146/annurev-med-062315-120245. Epub 2016 Nov 17. Annu Rev Med. 2017. PMID: 27860544 Review.
158 results