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Autotaxin impedes anti-tumor immunity by suppressing chemotaxis and tumor infiltration of CD8+ T cells.
Matas-Rico E, Frijlink E, van der Haar Àvila I, Menegakis A, van Zon M, Morris AJ, Koster J, Salgado-Polo F, de Kivit S, Lança T, Mazzocca A, Johnson Z, Haanen J, Schumacher TN, Perrakis A, Verbrugge I, van den Berg JH, Borst J, Moolenaar WH. Matas-Rico E, et al. Among authors: moolenaar wh. Cell Rep. 2021 Nov 16;37(7):110013. doi: 10.1016/j.celrep.2021.110013. Cell Rep. 2021. PMID: 34788605 Free PMC article.
Autotaxin: structure-function and signaling.
Perrakis A, Moolenaar WH. Perrakis A, et al. Among authors: moolenaar wh. J Lipid Res. 2014 Jun;55(6):1010-8. doi: 10.1194/jlr.R046391. Epub 2014 Feb 18. J Lipid Res. 2014. PMID: 24548887 Free PMC article. Review.
Structural basis of substrate discrimination and integrin binding by autotaxin.
Hausmann J, Kamtekar S, Christodoulou E, Day JE, Wu T, Fulkerson Z, Albers HM, van Meeteren LA, Houben AJ, van Zeijl L, Jansen S, Andries M, Hall T, Pegg LE, Benson TE, Kasiem M, Harlos K, Kooi CW, Smyth SS, Ovaa H, Bollen M, Morris AJ, Moolenaar WH, Perrakis A. Hausmann J, et al. Among authors: moolenaar wh. Nat Struct Mol Biol. 2011 Feb;18(2):198-204. doi: 10.1038/nsmb.1980. Epub 2011 Jan 16. Nat Struct Mol Biol. 2011. PMID: 21240271 Free PMC article.
Steroid binding to Autotaxin links bile salts and lysophosphatidic acid signalling.
Keune WJ, Hausmann J, Bolier R, Tolenaars D, Kremer A, Heidebrecht T, Joosten RP, Sunkara M, Morris AJ, Matas-Rico E, Moolenaar WH, Oude Elferink RP, Perrakis A. Keune WJ, et al. Among authors: moolenaar wh. Nat Commun. 2016 Apr 14;7:11248. doi: 10.1038/ncomms11248. Nat Commun. 2016. PMID: 27075612 Free PMC article.
Glycerophosphodiesterase GDE2 Promotes Neuroblastoma Differentiation through Glypican Release and Is a Marker of Clinical Outcome.
Matas-Rico E, van Veen M, Leyton-Puig D, van den Berg J, Koster J, Kedziora KM, Molenaar B, Weerts MJ, de Rink I, Medema RH, Giepmans BN, Perrakis A, Jalink K, Versteeg R, Moolenaar WH. Matas-Rico E, et al. Among authors: moolenaar wh. Cancer Cell. 2016 Oct 10;30(4):548-562. doi: 10.1016/j.ccell.2016.08.016. Epub 2016 Sep 29. Cancer Cell. 2016. PMID: 27693046 Free article.
Neuronal differentiation through GPI-anchor cleavage.
Matas-Rico E, van Veen M, Moolenaar WH. Matas-Rico E, et al. Among authors: moolenaar wh. Cell Cycle. 2017 Mar 4;16(5):388-389. doi: 10.1080/15384101.2016.1259894. Epub 2016 Nov 18. Cell Cycle. 2017. PMID: 27860541 Free PMC article. No abstract available.
197 results