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Lysosomal lipid alterations caused by glucocerebrosidase deficiency promote lysosomal dysfunction, chaperone-mediated-autophagy deficiency, and alpha-synuclein pathology.
NPJ Parkinsons Dis. 2022 Oct 6;8(1):126. doi: 10.1038/s41531-022-00397-6.
NPJ Parkinsons Dis. 2022.
PMID: 36202848
Free PMC article.
The Emerging Role of the Lysosome in Parkinson's Disease.
Navarro-Romero A, Montpeyó M, Martinez-Vicente M.
Navarro-Romero A, et al. Among authors: montpeyo m.
Cells. 2020 Nov 2;9(11):2399. doi: 10.3390/cells9112399.
Cells. 2020.
PMID: 33147750
Free PMC article.
Review.
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Mutant HTT (huntingtin) impairs mitophagy in a cellular model of Huntington disease.
Franco-Iborra S, Plaza-Zabala A, Montpeyo M, Sebastian D, Vila M, Martinez-Vicente M.
Franco-Iborra S, et al. Among authors: montpeyo m.
Autophagy. 2021 Mar;17(3):672-689. doi: 10.1080/15548627.2020.1728096. Epub 2020 Feb 24.
Autophagy. 2021.
PMID: 32093570
Free PMC article.
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Impaired proteasome activity and neurodegeneration with brain iron accumulation in FBXO7 defect.
Correa-Vela M, Lupo V, Montpeyó M, Sancho P, Marcé-Grau A, Hernández-Vara J, Darling A, Jenkins A, Fernández-Rodríguez S, Tello C, Ramírez-Jiménez L, Pérez B, Sánchez-Montáñez Á, Macaya A, Sobrido MJ, Martinez-Vicente M, Pérez-Dueñas B, Espinós C.
Correa-Vela M, et al. Among authors: montpeyo m.
Ann Clin Transl Neurol. 2020 Aug;7(8):1436-1442. doi: 10.1002/acn3.51095. Epub 2020 Aug 6.
Ann Clin Transl Neurol. 2020.
PMID: 32767480
Free PMC article.
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Clusterin deficiency is associated with a lack of response to teriflunomide in multiple sclerosis.
Malhotra S, Fissolo N, Rodríguez-Rivera C, Monreal E, Montpeyo M, Urcelay E, Triviño JC, Pérez-García MJ, Segura MF, Pappolla A, Río J, Vilaseca A, Fernández Velasco JI, Miguez A, Goicoechea C, Martinez-Vicente M, Villar LM, Montalban X, Comabella M.
Malhotra S, et al. Among authors: montpeyo m.
Clin Transl Med. 2024 Apr;14(4):e1654. doi: 10.1002/ctm2.1654.
Clin Transl Med. 2024.
PMID: 38591764
Free PMC article.
No abstract available.
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